value of pregnancy specific B1 glycoprotein [SP1] in maternal seru for the diagnosis of intra-uterine growth retardation [IUGR] in pre-eclampsia

Pregnancy specific glycoprotein [SP1] was estimated in the sera of 90 pregnant women in the third trimester [35 weeks]. 30 were normal pregnancy [control], 30 preeclamptic without clinical IUGR and 30 preeclamptic with clinical IUGR. The level of SP1 was significantly less in preeclamptic cases with IUGR compared to other groups. SP1 was able to diagnose 80% of cases with IUGR and 40.3% of cases with normal fetal growth. SP1 may provide a new index for the degree of fetal growth. It was suggested to use SP1 estimation for follow up of normal as well as preeclamptic pregnancies to detect IUGR in utero

effect of some non-steroidal anti-inflammatory agents on plasma glucose and insulin levels in non-insulin dependent diabetics

The effect of the non-steroidal anti-inflammatory drugs Piroxicam, Diclofenac sodium and Naproxen on plasma glucose and insulin levels was determined in thirty non-insulin dependent diabetics [NIDDM] patients with joint pains. A significant decrease in plasma glucose both in the fasting state and 2 hours post-glucose load was accompanied by a significant increase in plasma insulin levels

carboxyhemoglobin in industrial workers and its relation to blood lipids

The effect of carboxyhaemoglobin on blood lipids has been studied among 100 workers exposed to CO either in their working environment or because of being smokers or both, fifty non exposed workers served as controls. Serum cholesterol was found to be higher in the exposed group and it increased with increase in carboxyhaemoglobin level. Also serum betalipoproteins were higher among the exposed group and showed increase with the increase in carboxyhaemoglobin percent. The increased serum cholesterol and betalipoproteins in those exposed to carbon monoxide might lead to coronary atherosclerosis