Reaction of 6-bromo 2-cyanomethyl-3, 1-benzoxazine-4-one with amines

In our previous publication[1] the reaction of 2-cyancmethyl-3; 1-benzoxa-zin-4-one with amines was reported to afford 2-cyanomethyl- 4-quinazolines cyano group free 1,2,3,4-tetrahydro-2, 4-quinazolinediones following a decyanomethylation pathway. Consequently, it was found interesting to study the behaviour of 6-bromo-2-cyanomethyl-3, l-benzoxazin-4-one [III] towards a variety of amines