Effects of the crude extracts of Nigella sativa linn on isolated guinea-pig tracheal chain preparations

The aqueous extract of the seeds of Nigella sativa Linn. cause spontaneous relaxation on isolated tracheal chain preparations. The extract does not interact with the acetylcholine, but it inhibits the contractile actions of histamine on isolated tracheal chains. All the effects of N. sativa on isolated tracheal tissue preparations are found to be dose dependent