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Reductive debromination of erythro-2,3-dibromo-1-cyclopropyl-3- [p-substituted phenyl] -1-propanones
Alexandria Journal of Pharmaceutical Sciences. 1995; 9 (1): 43-46
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| IMEMR
| ID: emr-36145
RESUMO
Reductive debromination of erythro-2,3-dibromo-1-cyclopropyl-3-[p- substituted phenyl]-1-propanones was carried out with sodium thiophenoxide in 1: 2 molar ratio in absolute ethanol. All dibromides gave the same product; namely, trans-1-cyclopropyl-3-[p- substituted phenyl]-2-propanones. The configuration of the obtained products was assigned by PMR spectra. The possible reaction mechanism was presented