Comparative study of apoproteins A and B in diabetic and nondiabetic elderly

A clinical thesis was done to study the effect of diabetes mellitus on lipid profile of the elderly particularly apoprotein Al, being the major apoprotein of HDL, and apoprotein B, being the major apoprotein of LDL. The outpatient clinic of Geriatric department of Ain Shams University hospitals was chosen as a scene for this thesis. The lipid profile in diabetic elderly shown by this study is,. increase in cholesterol level, increase in triglyceride level, low HDL level, high LDL, low apo-Al level and increase in apoB as compared to non diabetic elderly. 25% of the diabetics in this study have high cholesterol level as compared to 10% in non diabetics. 15% of the diabetics have high level of'triglycerides as compared to only 5% of the non diabetics. 35% of diabetics have low HDL as compared to 10% in nondiabetics. As for LDL, 15% of the diabetics have high LDL level as comnpared to 5% of non diabetics, 20% of the diabetics tend to have low apo-Al level as compared to only 5% of the non diabetics. As for apoprotein B, 85% of the diabetics have normal level of apo-B, with only 10% of the diabetics having low level of apo-B as compared to 15% of non diabetics. However the mean level of apo-B among diabetics 96.4mg/dl was greater than among non diabetics 78. 7 mg/dl. There were sex variations of the lipid profile of both groups with the females having higher cholesterol, triglycerides, HDL and apo-Al levels and lower LDL and apo-B levels than males

Male psychogenic erectile dysfunction in elder ages: a myth or truth?

In advanced ages, erectile dysfunction as an increasingly encountered problem was thought to be organic in nature. The existing work had investigated its main etiologic aspects in 40 males, aged 56.2-65.9 years, suffering from secondary erectile dysfunction. Clinical psychiatric, neurological, and urological assessments were implemented, and supported by basic hormonal assays, blood glucose and lipids, urine analysis, and intra cavernous prostavasine injection. Cutaneous perception threshold, EMG of bulbocavernous reflex, Doppler ultrasonography, penile-brachial index, cavernosometry, and covernosography were performed for suspected cases. Multifactorial causation was identified in 22.5% of cases combined psychological and organic determinants were seized in 22.5% of subjects. and predominantly psychogenic etiology was involved in 32.5% of patients-mainly as depressive disorders according to DSM -111-R. Erectile dysfunction was predominantly neurogenic in 2.5%. Predominantly venogenic in 20% and predminantly arteriogenic in 2.5% of patients. Sexual hormonal deficiency was identified in 2.5% and systemic causes, namely hypertension, were evident in 17.5% of the study sample, the same as that of cases with bimixed origins. Different working mechanisms were discussed, and the current work proposed a diagnostic and therapeutic decision making tree, and provided recommendations that might be useful in clinical management of such cases