RESUMO
Fifty-nine patients undergoing major surgical operations are the subjects of this study. They were subdivided into: Control group of 30 patients infused with isotonic glucose and a study group of 29 patients infused with physiological saline. Blood transfusion was given when necessary, and each of the previous groups was classified into four subgroups, according to the amount of blood loss. Blood dilution was checked by haematocrit measurement. Pulse and blood pressure were monitored during the operative and post-operative periods. Determination of serum levels of proteins, HB, sodium, potassium, and chlorides were performed on the 2nd and 3rd subgroups pre- and post-operatively. The need for blood transfusion was observed and recorded and also the amount of fluid infused was calculated. The results revealed that cardiovascular stability was better maintained in patients receiving physiological saline, which greatly diminished the need for blood transfusion. There was no difference between the two groups in the frequency of complications. So, saline infusions can be given safely for two hours during major operations till the arrival of blood when indicated. Besides, post-operative hypotension is less frequent following saline infusions