Synthesis of some thiophosphoric acid esters derived from 4-hydroxy-4'-nitrobiphenyl and their azo-analogues as new biocides

Extending our work on organophosphates of potential biological activated, we have now prepared certain new biphenyl analogues 3b-d of the known insecticide parathion [Ia] [O,O- diethyl-O-p-nitrophenyl phosphorothioate; E 605][5], and the phosphonothionate ester EPN [Ib] [O-ethyl O-p-nitrophenyl benzenephosphonothionate][5] for toxicological evaluation

simple preparation of 3-hydroxy-4-methoxytetraphenylmethane

Methods known for the preparation of 3-hydroxy-4-methoxytetraphenyl-methane la are indirect and lengthy. During our work on the reaction of alkyl phosphites with 4-triphenylmc-thyM,2-benzoquinone [II], we endeavoured the synthesis of [la] by the action of diazomethane on 3, 4-dihyd-roxytetraphenylmethane [Ib]

Organophosphorus compounds: XXXVII On the reaction of dialkyl phosphites with isatins

The reaction of dialkyl phosphites with isatins[I], under different experimental conditions, gives the corresponding dioxindole c-3-phosphonic esters [TH]. Similarly, naphtho [2, 1-b]furanl -2-dione [IV] reacts with dimethyl and diethyl phosphites to the alpha hydroxyphor.phonates-[Va] and [Vb], respectively structural assignments are based oil IR, [1]H NMR, [31]P NMR and mass spectrometric results

Reaction of thiobenzophenone with fluorenylidene triphenylphosphorane and fluorenylidene triphenylarsinane

Benzophenone was found to be uncreative towards flourenylidenetriphenylphorane and flouenylidentriplienylarsinane [1]. However, although thiobenzophenone [I] is known to react with benzylidenetriphenylphosphorane [2], yet its behaviour towards the aforementioned stable| yields has not yet been reported. This motivated our interest and indeed we have found that thiobenzophenone [I] reacts readily with fluorenylidenetriphenylphosphorane [IIa] and 2,7 -dibromo-derivative [.[IIb] in dry benzene at room temperature to yield the 9-substituted fluorenes IVa and IVb, respectively. Triphenylphosphine sulphide [Va] was isolated in both reactions in a quantitative yield

Synthesis of dialkyl [2-0 carbamoyl-3,4,5,6-tetrachlorophenyl] phosphates and dialkyl [4-0-carbamoyl-2,3, 5,5,6, tetrachlorophenyl] phosphates as new biocides

ORGANOPHOSPHATES have attracted much interest by virtue of the wide potentialities they possess. Thus they find application as insecticides[1] fungicides[2] and as herbicides [3]. Meanwhile, carbamates are well known for their broad biological activity[4-9]. This prompted us to prepare a number of new compounds, derived from tetrachlorobenzoquinones, encorporating both the phosphoric-, and carbamic acid-ester moieties to examine their biological activity. The phosphate adducts IIIa-c and IVa-c were prepared according to established procedures[10-11] by reacting dialkyl phosphites with tetrachloro-o-benzoquinone [I] and tetrachloro-p-benzoquinone [II] respectively, in the presence of triethylamine