Immunohistochemical study of Non-Hodgkin Lymphoma presenting in head and neck region

Thirty-four patients with NHL presenting in the head and neck region were studied clinically, histologically and by immunohistochemistry using the B-cell markers, T-cell markers, histocytic markers and transferrin markers. The peroxidase antiperoxidase technique was adopted. According to the immunologic phenotypes, 19 cases were B- cell, 7 cases were T-cell, while 7 cases were null. The immunohistochemistry was very helpful in diagnosing high grade lymphomas, especially the undifferentiated and histocytic types

Reconstruction of mandibular defects using hydroxyapatite veterinary bone graft

A 1 cm piece of m and ible was resected in 6 rabbits and replaced by an equal graft of a newly developed material [veterinary porous hydroxyapatite [VHAP]]. X-ray studies were done preoperatively, immediate postoperatively as well as at 1, 2 and 3 months later. It was evident radiologically that the material was completely united to the host bone after 3 months. The rabbits were sacrificed at 6 weeks and 3 months [3 rabbits each] and the m and ible was examined by scanning electron-microscopy which showed complete integration of the graft in the host bone. Also, the chemical structure of the graft was studied by infrared spectrographs. Clinically, the graft was completely incorporated in the m and ible without any complications. One can suggest using material in human to reconstruct post-surgical m and ibular defects

Endoscopic retrograde cholangiography in postoperative common bile duct injury: value before corrective surgery

27 patients with common bile duct injury were studied by endoscopic retrograde cholangiography. The type and site of injuries were identified in most cases; full length of injury was outlined. In 17 patients the duct was ligated and in 10 there was stricture mostly at the level of cystic duct stump. Endoscopic retrograde cholangiography is a safe and reliable diagnostic tool, whenever postoperative common bile duct injury is suspected. It gives the surgeon as well as the physician a real picture of the problem and helps them in deciding the type of corrective surgery

Choledochal obstruction by a stone impacted at the mouth of cystic duct: a variant of Mirizzi Syndrome

Three patients with high grade common bile duct obstruction from an impacted stone at the cystic duct juncture are described. All cases were diagnosed preoperatively by direct endoscopic retrograde cholangiography. A low lying cystic-choledochal duct junction with contiguity of a large cystic duct with the common hepatic duct were present in one patient only. However, in the other two, a radiolucent stone [medium sized], just about to be prolapsed from cystic duct mouth was documented with much dilated cystic duct as well as common hepatic and intrahepatic ducts. The findings indicated that even in the absence of low lying cystic-choledochal duct juncture, a variant of Mirizzi syndrome can occur

Study of hydroxyproline content in cases of sliding hiatal hernia

The hydroxyproline content, which is an accurate measure of collagen content, was measured in 12 cases of proved sliding hiatal hernia and 6 control cases. These samples were taken from the phreno- esophageal ligament and the diaphragmatic crus. It was significantly lower in the phreno-esophageal ligament of patients compared to controls [38.9 +/- 6.1 Ug/mg dry tissue and 45.3 +/- 6.2 Ug/mg dry tissue, respectively] and significantly lower in diaphragmatic crus in studied patients as compared to controls [50.6 +/- 10.5 Ug/mg dry tissue and 66.3 +/- 2.4 Ug/mg dry tissue respectively]. This abnormal lower hydroxyproline content in both phreno-esophageal ligament and diaphragmatic crus may clarify their anatomical role in the pathogenesis of sliding hiatal hernia. The weakness of these structures is due to defective collagen, which should be considered during hiatal hernia repair

Caeruloplasmin and transferrin as tumour markers in epidermoid carcinoma of head and neck

Estimation of ceruloplasmin and transferrin were performed on 26 subjects, 16 cases of epidermoid carcinoma of head and neck and 10 healthy controls of matched age and sex. Significant rise of ceruloplasmin was noted in patients; however, there is no relation between the duration of the neoplasm and the ceruloplasmin level. While, transferrin was insignificantly lower in cancer patients than in control