RESUMO
Herbal medicine has been regarded as a safer and more natural method to promote health and alleviate illness and has gained notable popularity. Plants continue to be the primary source of new chemicals and drugs and hence play a pivotal role in the continual improvement in therapeutic medicine. India has a huge asset of indigenous plants and minerals which have been broadly used for therapeutic claim. One such plant which has immense benefits derived from it is Cissus quadrangularis [CQ] colloquially known as hadjod or pirandai. CQ is one of the most significant plants. However, practically the entirety of its parts are utilized in medicine among which seeds, stems, roots, and shoots are the most significant parts. Concentrates and powders of Cissus quadrangularis have been utilized for a long time to aid bone and tissues healing, as an antioxidant, for relieving pain & swelling, to fight against infection, as an anabolic, and also to help in weight reduction. The most important usage has been for bone regeneration and fracture healing. Numerous studies have been done to prove its pharmacological effects and to substantiate its use clinically. The aim of this review is to elaborate on CQ, its ethnopharmacology, phytochemistry and principle constituents, pharmacological actions, formulations and to review previous literature such as animal studies, in vitro studies and clinical trials to understand in detail about the applications of this plant in medicine and dentistry