Antibiotic resistance in pseudomonas aeruginosa [aztreonam versus others]

This study was done in the Bacteriology Department, Faculty of Medicine, Zagazig University, during the year of 1991 on 116 clinical strains of P. aeruginosa isolated from Zagazig University Hospital. The study aimed to evaluate the efficacy of aztreonam, the first member of a new class of antibiotics, monobactams, in P. aeuroginosa infections compared with a number of antibiotics currently used to treat P. aeruginosa infections by determination of the minimum inhibitory concentration [MIC] using the agar dilution method. The study revealed highly significant statistical values [p < 0. 001] in resistance of P. aeruginosa to all groups of antibiotics compared with aztreonam