Parotid gland tumors: a retrospective study of 154 patients / Tumores de glândula parótida: estudo retrospectivo de 154 pacientes

INTRODUCTION: Benign tumors of the parotid gland comprise the majority of salivary gland tumors. OBJECTIVE: To review the clinical characteristics of parotid gland tumors submitted to surgical treatment by the same surgeon. METHODS: Retrospective study with 154 patients who had parotid gland tumors. Clinical and histological data, type of surgery, and complications were assessed and described. RESULTS: The main manifestation was a mass with a median evolution of 12 months for benign tumors and five months for malignant tumors. Ultrasonography was the most frequent complementary exam. Pleomorphic adenoma was the most common of the benign tumors, and mucoepidermoid carcinoma was the most frequent malignant tumor. Superficial parotidectomy with preservation of the facial nerve was the most common surgical procedure and reversible paresis of branches of the facial nerve was the most common complication. CONCLUSIONS: Pleomorphic adenoma is the most common parotid gland tumor and superficial parotidectomy with preservation of the facial nerve is the most common and appropriate treatment for most low-morbidity tumors. .

INTRODUÇÃO: Os tumores de parótida são frequentemente de natureza benigna e correspondem à maioria dos tumores de glândulas salivares. OBJETIVO: Revisar as características clínicas de neoplasias de parótidas submetidas a tratamento cirúrgico pelo mesmo cirurgião. MÉTODO: Estudo retrospectivo, onde foram avaliados 154 pacientes com neoplasia de parótida. Dados clínicos, histológicos, tipo de cirurgia e complicações foram compilados e descritos. RESULTADOS: A principal manifestação foi a de uma massa tumoral com uma mediana de tempo de evolução de 12 meses para os tumores benignos e 5 meses para os tumores malignos. A ecografia foi o exame complementar mais indicado. Dentre os tumores benignos, o adenoma pleomórfico foi o mais comum e o carcinoma mucoepidermóide o mais frequente dentre os malignos. A parotidectomia superficial com preservação do nervo facial foi a cirurgia mais indicada e a paresia reversível de ramos do nervo facial, a complicação mais prevalente. Conclusões: O adenoma pleomórfico é o tumor mais comum da glândula parótida e a parotidectomia superficial com preservação do nervo facial é o tratamento mais adequado para a maioria dos tumores de baixa morbidade. .

An experimental model of chronic rhinosinusitis in rabbits without bacterial inoculation

PURPOSE: Evaluate and compare two different experimental techniques of maxillary sinus ostium occlusion using N-butyl cyanoacrylate in developing chronic histological findings without the inoculation of pathogenic bacteria among rabbits. METHODS: In a randomized study, sixteen New Zealand rabbits were assigned for occlusion of the right maxillary sinus through a transmaxillary approach or through the roof of the nasal cavity. The contralateral sinus served as a control. After 12 weeks, the animals were sacrificed for blinded histopathological analysis of the maxillary sinus mucosa. RESULTS: Histopathological changes consistent with CRS were found in eight (100%) of the maxillary sinuses approached transmaxillary and three of those through the roof of the nasal cavity (37.5%), p 0.008 and 0.250, respectively, comparing with the control side. Chronic mucosal changes were significantly better induced using the transmaxillary approach (p 0.026). CONCLUSION: It is possible to induce a model of chronic sinusitis among rabbits with transmaxillary sinus occlusion without bacterial inoculation. This model can be replicated for future cellular studies. .