Influence of maternal anemia on placental volume with study of uterine artery doppler

To study the influence of maternal hematocrit [Ht] and hemoglobin [Hb] level on placental volume with study of uterine artery Doppler. In this prospective study 40 pregnant [singleton pregnancy] cases were selected from the outpatient clinic of Alzahra university Hospital. They were divided into two groups the study group [20 cases] were anemic[iron deficiency] and the control group[20cases] were healthy. For each case two scans for the placenta and fetal growth were performed, the first at recruitment and the second 5 weeks later. Placenta volume was measured at each visit using three dimensional ultrasound. The maternal Hb and [Ht] were measured in each visit. It revealed a non statistical significance between maternal hemoglobin, hematocrit and placental volume during the 1[st] visit and 2[nd] visit in anemic group compared to the control group. As regards Doppler study of the uterine artery in the present study it was noted that the pulsatility index and resistance index showed a non significant increase in the anemic group compared to the control group. Maternal iron deficiency anemia can affect placental growth and development. Placental volume increased with mild anemia during the first trimester but has no significant effect of fetal growth. The use of 3D ultrasound is more accurate and efficient safe technique of great value in evaluating placental growth and volume. Also, the study of uterine artery blood flow during the mid second trimester showed a non significant increase of RI and PI with maternal anemia. Further study are needed for the effect of anemia on fetal growth during preconceptional, first, second, third trimester and the outcome of pregnancy

Selenium deficiency and ovarian tumors

The objective of this study was to investigate a possible link between selenium deficiency and problems of ovarian tumors aiming to understand the nutritional status and solve some of the health problems. Serum selenium levels were measured in 60 Egyptian women divided into two groups. Selenium levels in women of group II showed significantly lower values than women of group I. A significant decrease was found in women of group II than the other studied women

Circulating endothelial cell adhesion molecule E-selectin in pre-eclampsia: relationship to its severity

This study was conducted to demonstrate the role of cell adhesion molecule E-selectin in preeclampsia and to asses if there are changes in its level with varying degrees of preeclampsia. Serum E- selectin concentration was measured in ten healthy normotensive pregnant women [group one], 20 cases with mild preeclampsia [group two] and 20 cases with severe preeclampsia [group three] in late third trimester of pregnancy. E-selectin concentrations were significantly higher in the preeclampsia groups compared with the control group. On the other hand, its concentrations were higher in severe than mild preeclampsia [53.74 + 24.82 and 65.60 + 37.57 ng/ml, respectively] but the difference did not reach a statistical significance. Within the preeclampsia subgroups, serum concentration of E-selectin was higher in severe cases exhibiting fetal growth retardation compared with mild preeclampsia. There was a significant positive correlation between E- selectin concentrations and diastolic blood pressure in severe preeclampsia group. It was concluded that the elevated levels of E- selectin in pregnant women with preeclampsia supported the concept of a primary endothelial cell involvement in the pathogenesis of preeclampsia. Measurement of this adhesion molecule may be useful in monitoring pregnancies with respect to the development of preeclampsia