RESUMO
Background: Sickle cell anemia is an autosomal structural defect that affect the hemoglobin. It is associated with reduction in the RBC life span especially under stress. As a result of this structural defect the RBCs takes a sickle shape which is associated with a lot of complications that significantly have an effect on the patient's life
Objective: In this study, we aim at evaluating the most common complication of sickle cell anemia. Also, the assessment of the various management plans to prevent it if occurred
Methods: PubMed database were used for articles selection as well as all relevant articles to our research interest with the following topics: Sickle cell anemia, Complications, Mortality, Prevention and Management. We excluded other articles, which are not related to this field. The data were extracted according to specific form in which it is going to be reviewed by the group members
Conclusion: Sickle cell anemia have various complications that have impact on quality of life and arise from effect of three main pathophysiological mechanisms i.e. Vasooclussive, hyper-haemolytic and infective complications. Hydroxyurea, chronic blood transfusion, and routine Transcranial Doppler Ultrasound are still the most useful preventive measures of SCA complications
RESUMO
Background: Acne is a widespread and complex skin disease among developed nations, affecting nearly all young adults between the ages of 15 to 17 years. It is a chronic inflammatory skin disorder resulting in psychological stress. Historically, the relationship between diet and acne is controversial. As a result, significant studies have been done to evaluate this relationship. Assessment of these literatures will help to provide better outcomes for the patients
Objective:This study aims to: 1- Measuring effect of diet and nutritional substances in the management and prevention of acne vulgaris. 2- Providing a reference paper analyzing all the clinical studies in this field. 3- Analyzing the last progression has been reached
Methods: PubMed database was used for articles selection. We included all relevant articles to our review with the following topics [["Acne Vulgaris/diet therapy"[Mesh]] AND ["Acne Vulgaris/prevention and control"[Mesh]]] AND ["Acne Vulgaris/therapy"[Mesh]]. We excluded other articles which are not related to this field. The data will be extracted according to specific form in which it is going to be reviewed by group members to assess the dietary effect of nutritional substance on acne vulgaris
Conclusion: We concluded that there are studies that showed promising results among patients and proved that associations do exist. Nevertheless, further studies with bigger sample and better protocols are needed to establish a concrete evidence-based relationship