Effect of Atorvastatin on blood and gasometrical parameters in patients with COPD: a double-blind controlled clinical trial

Chronic obstructive pulmonary disease [COPD] is a syndrome with progressive and irreversible airflow limitation. The aim of this study was to evaluate the effect of Atorvastatins on blood parameters including blood gasses in patients with COPD. This randomized double-blind, controlled clinical trial study was conducted on the case and control groups of patients with COPD in Vali-e-asr hospital in Birjand in 2015

In the laboratory, 15 cc of venous blood was taken from each subject. Initial tests included white blood count [WBCs], hemoglobin[Hb], PH, and Pco 2. O2 saturation was observed at rest by means of Pulse Oximeter for the duration of one minute and the highest value was recorded. Out of the 34 patients, 18 cases [52.9%] were treated by atorvastatin and 16[47.1%]. . received conventional treatment Mean age of the atorvastatin and control group was 65.8 +/- 11.5 and 63.7 +/- 7/6 years, respectivly. The case group showed a significant decrease in mean count of WBC and hemoglobin, but increase in O2 saturation after intervention. In conclusion, it can be concluded that taking atorvastatin has a significant impact on the reduction of hemoglobin and increase of oxygen saturation in COPD patients, which requires further studies

Tuberculosis of the breast: a case report

Primary tuberculosis of the breast is a rare disease. It usually occurs in female of reproductive age. Any form of tuberculosis mastitis may present with feature of malignancy. Diagnosis is mainly based on identification of tubercle bacilli. We report a 42-year-old woman with primary tuberculosis abscess of the breast, who underwent surgical resection. Fine needle biopsy failed to achieve specific diagnosis before surgical operation. She responded to anti-TB therapy postoperatively. In endemic area, tuberculosis should be considered in the differential diagnosis of breast tumors

Primary tuberculosis of the breast: a case report

Background and Purpose: Clinical appearance of tuberculosis is very variable and it may be presented with any form. Tuberculosis, in Iran, is a very common disease and it is differential diagnosis of many diseases. Mammary Tuberculosis is a rare site of extrapulmonary TB. It may be primary or secondary

The patient: A 42-year- old woman, presented with breast swelling, pain and Skin ulcer of one month earlier was treated with surgery and antibiotic therapy for breast abscess without success

Methods: When she presented, she complained of erythema and discharge of med. Lateral of breast. Para-clinic tests and Chest-X-Ray was normal. All nectotic tissue was removed and biopsy was done. Pathology provided the diagnosis of Tuberculosis. An anti-Tuberculosis regimen was prescribed for 6 months

Conclusion: Tuberculosis is rarely localized in the breast. The main differential diagnosis is breast cancer. Pathology examination is required for diagnosis. Successful treatment is a combination of antituberculous drug therapy with the removal of infected breast tissue