A Review of Human Myiasis in Iran With an Emphasis on Reported Cases

@#Myiasis is the invasion of organs and tissues of humans or other vertebrate animals by fly larvae. The first reported case of myiasis in Iran was ophthalmic myiasis, which was reported in 1975. Since then about 81 cases of human myiasis have been reported in Iran up till 2017. According to this study, all types of myiasis were reported from different parts of Iran. Vectors species of human myiasis in Iran are: Oestrus ovis, Chrysomya bezziana, Dermatobia hominis, Hypoderma bovis, Rinoestrus purpureus, Lucilia serricata, Eristalis tenax, Sarcophaga haemorrhoidalis, Sarcophaga fertoni, Wohlfahrtia magnifica, Wohlfahrtia nuba, Wohlfahrtia vigil, Cynomyopsis cadaverina, and Psychoda albipennis. There were two age peaks of myiasis infection in Iran: 21- 40 years old, and 65 years old . Specific and primary treatment is removal of larvae from infected tissues . Ironing is an effective way to eliminate eggs, also wearing long sleeve clothes to cover wounds and avoiding outdoor sleep are another way to prevent infection with flying larva. The aim of this review was to determine the prevalence of myiasis in different parts of Iran in order to determine and prioritize the methods of control based on the results.

effect of apple juice on antioxidant enzymes and lipid profiles in orchidectomized rats

The age-dependent worsening of lipid profiles increased the risk of cardiovascular disease in males. Eating fruits and vegetables is known to be beneficial on lipid profile. The objective of this research was to delineate whether drinking daily squeezed apple juice [AJ] modulates lipid profile and antioxidant enzymes in the animal model that gonadectomized. In this experimental study, 28 male rats were equally divided among the following 4 groups: group I [control], orchidectomized [ORX], ORX +AJ 10%, and ORX+ AJ 25%. After 60 days of drinking AJ, superoxide dismutase [SOD], alkaline phosphatase [ALP], cholesterol, LDL, HDL and triglycerides in serum were evaluated. Data analyzed by SPSS-16 and computed using one way ANOVA followed by Tukey multiple comparison test. P < 0.05 was statistically significant. In the ORX group compared with the sham group serum SOD and ALP activities decreased [P < 0.05], while serum cholesterol, triglycerides, LDL increased but HDL decreased in ORX groups [P < 0.05]. In contrast to the ORX group, drinking AJ decreased [P < 0.05] concentration of LDL, TG and cholesterol in the serum. AJ also increased [P < 0.05] serum HDL, SOD and ALP activities compared with the ORX group

potential of honey to promote wound healing in periodontology: a pilot randomized clinical trial

Honey has been used as a nutraceutical in many traditional and ancient remedies. Considering well documented benefits of honey to accelerate wound healing, for the first time we aimed to assess intra oral surgical wound healing process with honey. We designed a pilot randomized placebo controlled cross-over clinical trial. Patients who required bilateral Modified Widman Flap [MWF] surgery randomly assigned to receive either 15 cc topical Persian Thymus Vulgaris concentrated honey three times a day or normal saline as placebo with the same amount at the site of the surgery for seven consecutive days. After a 35-day wash-out period the study groups were crossed. The primary efficacy outcome was changes in healing index [Landry index] and the secondary efficacy outcome were changes in gingival and plaque indices [Loe and Sillness, Sillness and Loe indices]. It also includes safety issues consisting of any allergic reaction, delayed healing or wound dehiscence. Ten patients enrolled with the mean age of 36 [ +/- 1.5] ranged between 35-40 yrs. There was a significant improvement in wound healing considering time and treatment effects in both groups, although faster wound healing observed in honey treated patients [P<0.001]. In both groups gingival indices were noticed to be improved by the time during the first phase of the study. Both groups displayed aggravated Plaque formation; nevertheless it was merely statistically significant in the control group [F [3, 27] =12.88, P value < 0.001]. All wounds healed normally and no adverse events recorded. Our study established the safety, efficacy and feasibility of topical honey to promote periodontal surgical wound healing. [IRCT138901192547N2]