RESUMO
Background and Objectives: there are different anesthetic methods for hemodynamic stabilization during lumbar disc surgery. Anesthesias with intravenous drug including propofol-remifentanil and isoflurane have acceptable results inthis regard. In this study we compared the hemodynamic effects of these two anesthesia methods in patients, candidate for lumbar disc surgery
Materials and Methods: in this study, 70 patients, who were candidate for lumbar disc surgery underwent general anesthesia using propofol-remifentanil or isoflurane. After induction with lidocaine, propofol and sisatracorium, anesthesia was maintained in isoflurane group with controlled respiration using oxygen and N20 with 50% ratio with isoflurane l% and in propofol-remifentanil group, with controlled respiration using 100% oxygen with propofol 5 mg/kg/h and remifentanil 0.125 [micro]g/kg/min. Hemodynamic findings during surgery and after surgery were recorded in both groups
Results: there were no significant differences between groups in their systolic and diastolic blood pressure, heart rate and oxygen saturation. Also, both groups were similar in their return to spontaneous breathing and extubation, time for eye opening and ability of verbal communication, meanwhile, frequency of general presentations such as chill, agitation, degree of post-surgery hypoxia. Nausea and vomiting were not significantly different between two groups
Conclusion: anesthesia with both methods; intravenous propofol-remifentanil or inhaled isoflurane in patients who are undergoing lumber disc surgery regarding to heir hemodynamic effects such as hypotension and brady cardia are acceptable
RESUMO
To compare two different doses of propofol for laryngeal mask airway [LMA] insertion in children undergoing out-patient surgeries. Insertion of LMA just after anesthesia induction is facilitated using propofol. However, the optimal dose of this drug not determined yet as heavy doses may lead to severe complications, whereas lower doses may not be quite as effective. In a double-blind randomized clinical trial, 120 children undergoing out-patient surgeries were recruited to receive intravenous propofol at a dose of either 2.5 mg/kg [group 1] or 3.5 mg/kg [group 2] for induction. Intravenous midazolam [0.03 mg/kg] and fentanyl [1 microg/kg] were used as pre-medication in all patients and anesthesia induction was initiated using lidocaine [1 mg/kg] prior to propofol administration. Hemodynamic changes, probable complications, quality of the established airway and number of attempts for LMA insertion were compared between two groups. There were no differences in systolic and diastolic blood pressure, heart rate, peripheral oxygen saturation and intraoperative complications between the groups [P>0.05]. LMA insertion was successful at the first attempt in 55 [93.2%] and 54 [91.5%] cases in group 1 and group 2, respectively [P>0.05]. The efficiency of the established airways was adequate in all the patients of both groups. It seems that propofol doses of 2.5 and 3.5 mg/kg are equally effective for LMA insertion following intravenous midazolam, fentanyl, and lidocaine