Causes and clinical forms of cutaneous adverse drug reactions in patients referred to Farshchian Hospital in Hamedan in 2008 and 2009

Adverse drug reactions are inevitable 1 outcomes of drug therapy, which may cause mortality and | morbidity for those whom are treated in this way. Cutanous adverse drug reactions are abserved in 2% to 3% of inpatients but only 2% of them are considered serious and may cause death. The aim of this study was to determine the cause and clinical forms of adverse drug reactions referred to department of dermatology. This cross-sectional study that was done on patients with diagnosis of cutanous adverse drug reactions in 2007 and 2009. All patients suspected with diagnosis of adverse drug reactions were examined by an experienced dermatologist for determination of different kinds of clinical manifestations. During the study period, 308 patients were recruited. Cutanous adverse drug reactions were found to be more frequent in females [63%] than in males [37%]. Betalactam antibiotics were found to be the most frequent cause off adverse cutaneous drug reactions [42.7%], followed by non- 1 steroidal anti-inflammatory drugs [16.5%]. Acute urticaria I was the most frequent observed drug reaction [59.2%] followed by fixed drug eruption [18.5%] and maculopapular rashes [14.9%]. In this study adverse cutaneous drug reactions was mainly induced by betalactam antibiotics and non-steroidal anti-inflammatory drugs. The most common forms of cutaneous adverse drug reactions were found to be: acute urticaria, fixed drug eruption and maculopapular rashes

case report of a giant skin tag

Skin tags are skin-colored, asymptomatic, pedunculated lesions located at the neck, axillae or groin. It affects any age, including infants. We report a 60-year-old Iranian woman with a giant pedunculated skin tag on the left thigh for 10 years. It measured 10 cm in length and 7 cm in width, distally

Frequency of hepatitis C virus antibody in lichen planus patients admitted to dermatology ward of Sina hospital, Hamedan, Iran from 2002 to 2004

An epidemiological association of lichen planus [LP] with hepatitis C virus [HCV] infection has been found only in certain parts of the world and in some countries no association has been noted. The present study was done to evaluate the association of LP with HCV in patients admitted to Sina hospital, Hamedan, Iran from 2002 to 2004. The presence of anti HCV antibody in 32 patients with LP was compared with 43 patients suffering from other dermatoses not related to HCV. Both patient and control groups were screened for the anti HCV antibody using ELISA. The positive cases were tested again using RIBA method. Only confirmed positive cases with the RIBA method were considered as anti HCV antibody positive. Anti HCV-antibody was positive in 3.1% of patient group [one out of 32] and in 7% of control group [3 out of 43]. In Hamedan province no association was found between HCV infection and LP therefore the routine test of LP patients for anti HCV antibody is not necessary