Association between endometriosis and hyperprolactinemia in infertile women

The association of endometriosis with hyperprolactinemia is controversial. The present study aimed to determine the frequency of endometriosis and association of prolactin with endometriosis in infertile women. 256 infertile women who underwent diagnostic laparoscopy for the evaluation of infertility, referred to Fatemezahra Infertility and Reproductive Health Research Center were included in a cross-sectional study. The presence of endometriosis was evaluated. To investigate the association of endometriosis with hyperprolactinemia, the patients whose infertility was not caused by endometriosis were included as control group. Serum prolactin [PRL] level was measured in both groups. The comparison of basal serum PRL levels between the two groups was performed, using independent t-test. One way ANOVA was used to determine PRL association with endometriosis stages. The frequency of endometriosis was found to be 29%. PRL levels were significantly higher in endometriosis group compared to control group [23.02 +/- 1.25 vs. 17.22 +/- 1.22 respectively, p=0.004]. Statistically significant associations were found between staging of endometriosis and prolactin levels [p=0.01]. Hyperprolactinemia may be associated with endometriosis and its progression

[Comparison of calcium,phosphor,total protein and antioxidant levels during pregnancy]

Background and Aim: Hurmonal changes during pregnancy can change many organs of the body such as oral cavity and saliva . The purpose of this study was to compare of calcium, phosphor and total protein and antioxidant levels of pre-pregnancy and each trimester of pregnancy

Materials and Methods: 30 women referring for consultation with gynecologist were selected for this semi-experimental study. Their whole unstimulated saliva was collected at that session and at every trimester. The salivary composition mentioned above was measured by spectrophotometry. Data was analysed by repeated measure test and and paired t-test

Results: There was significant difference in phosphor, protein , total antioxidant level of saliva in pre-pregnancy and during pregnancy [p<0/01],[p= 0/01] respectively. There was no significant difference in salivary calcium rate of pre-pregnancy and during pregnancy .[p=0/08]

Conclusion: During pregnancy the rate of salivary phosphor and total antioxidant was increased. Protein level was decreased but calcium level was not changed