RESUMO
Background: Diabetes is one of the most common metabolic disorders and is related to oxidative-stress-induced diseases. Given the role of dietary antioxidants in the control and prevention of diabetes, this study aimed to examine the effects of sesame butter versus sesame oil on the serum levels of glucose, lipid profile, and oxidative stress biomarkers in diabetic rats
Methods: Forty male albino rats of Wistar strain were randomly divided into 4 groups [i.e., nondiabetic control rats, diabetic rats, diabetic rats treated with sesame butter, and diabetic rats treated with sesame oil]. Experimental diabetes was induced with an intraperitoneal injection of streptozotocin [55 mg/kg]. Sesame butter [1.25 g/kg] and sesame oil [0.5 g/kg] were given by oral gavage to the diabetic rats for 6 weeks. Finally, serum glucose, lipid profile, total antioxidant capacity [TAC], and malondialdehyde [MDA] levels were measured and analyzed statistically
Results: Our data showed that the diabetic groups treated with sesame butter and sesame oil had significantly lower levels of glucose and higher levels of high-density lipoprotein than did the diabetic control group at the end of the study [P<0.05]. Sesame butter supplementation also increased TAC and decreased MDA concentrations significantly in the diabetic rats [P<0.05]
Conclusion: The antihyperglycemic, antioxidative, and partly lipid-lowering effects of sesame butter make it an excellent candidate for future human studies on diabetes, although further research is needed to determine the exact dose and duration of supplementation
RESUMO
To assess the association between dietary patterns, central obesity, and blood pressure [BP]. In this cross-sectional study, we evaluated anthropometric measurements, BP, and usual dietary intakes of 243 men, aged 30-50 years old, working at the Education and Culture Systems in Ahvaz, Iran, between October 2011 and March 2012 using the Food Frequency Questionnaire [FFQ]. Using the factor analysis, we extracted 3 major dietary patterns: [prudent], [high protein] and [high fat]. After controlling for confounders [energy and physical activity], [prudent] pattern scores were negatively associated with body mass index, waist circumference, waist-to-hip ratio, systolic and diastolic BP [p<0.05]. Scores of [high protein] and [high fat] patterns were positively related to obesity and hypertension indices [p<0.05]. A dietary pattern characterized by high consumption of vegetables, fruits, poultry, fish, low-fat dairy products, whole grains, nuts, and olives are associated with lower risk of central obesity and hypertension, while dietary patterns with high amounts of red meat, egg, butter, high fat dairy products, hydrogenated fats, pizza, and soft drinks are associated with increased risk of these conditions in Ahvaz, Iran
RESUMO
Background and purpose: Diabetes is one of the most common endocrine metabolic disorders, resulting from defects in insulin secretion, insulin action, or both. According to the useful properties of sesame and extensive use of its products [like sesame butter] in Khuzestan province, the purpose of this study was to investigate the effects of sesame butter vs. sesame oil on serum glucose levels and lipid profiles on diabetic rats.
Methods: Forty male rats of Wistar Strain were randomly divided into 4 groups [10 rats per group] and were being treated for 6 weeks as follows: Group 1: non diabetic control rats; Group 2: diabetic control rats; Group 3: diabetic rats that were being treated with 1.25 g/kg sesame butter; and Group 4: diabetic rats that were being treated with 0.5 g/kg sesame oil. At the end of the experimental period, serum levels of glucose and lipid profiles were measured. The statistical analysis was carried out, using SPSS 18 software. One way analysis of variance [ANOVA] and Independent sample test were used to compare means between the treated and controlled groups. P< 0.05 was considered as significant.
Results: Utilization of sesame butter and sesame oil in diabetic rats's regime caused a significant decrease in glucose concentrations and also led to increase in high density lipoprotein-c levels compared to the diabetic control rats [P<0.05]. Triglyceride levels were also decreased after 6 weeks in the sesame oil treated diabetic group [P=0.000].
Conclusion: The results of presented study indicate the improving effects of sesame butter and sesame oil on controlling glucose levels and lipid profiles in the animal models of diabetes.
RESUMO
There is little information regarding relationship between maternal dietary pattern and infant anthropometric parameters at birth. This study was carried out to determine relationship between dietary patterns in pregnancy with infants' anthropometric parameters. In this cross-sectional study, 94 pregnant women [GA: 37-40 weeks] referred to Ahvaz Razi hospital were selected. Anthropometric parameters were measured. The dietary intakes were assessed using a semi-quantitative food frequency questionnaire. Factor analysis was used to identify dietary patterns. Statistical analysis was done in the SPSS. In this study, three major dietary patterns including [healthy], [traditional] and [western] dietary patterns were identified. After adjusting of confounders [age, physical activity, energy intake, pregnancy weight gain and infant sex], the relationship between dietary patterns with birth weight, height and head circumference were exhibited in three models. The relationship between healthy dietary pattern and infant weight, height and head circumference at birth was significantly positive in all models [P0<05]. Western dietary pattern had significant negative relationship with head circumference in the model 1 and 2. Moreover, it had negative relationship with birth weight in the model 1 [P0<05]. Traditional dietary pattern did not show any significant relationship with anthropometric parameters at birth. The present study found significant relationship between maternal dietary patterns with anthropometric parameters at birth. Further prospective studies are suggested to confirm the findings