RESUMO
Because of the unobvious early symptoms and low 5-year survival rate, the early diagnosis and treatment is of great significance for patients with non-small cell lung cancer. Glucose transporter-1 is the most widely distributed glucose transporters in various tissue cells in the human body, whose expression in non-small cell lung cancer is closely related to the histological types, lymph node metastasis, degree of differentiation, progression and prognosis.
Assuntos
Humanos , Carcinoma Pulmonar de Células não Pequenas/diagnóstico por imagem , Fluordesoxiglucose F18 , Proteínas Facilitadoras de Transporte de Glucose , Transportador de Glucose Tipo 1 , Neoplasias Pulmonares/diagnóstico por imagem , Tomografia por Emissão de Pósitrons combinada à Tomografia Computadorizada , Tomografia por Emissão de Pósitrons , Compostos RadiofarmacêuticosRESUMO
Objective To investigate the relationship between Sjgren′s synd rome and associated other skin diseases. Methods Clinical features, laboratory a nd histopathological findings and causes were analyzed retrospectively in 13 cas es of Sjgren′s syndrome. Results Thirteen patients were studied, including 1 male and 12 female, the mean age of onset was 35.3 years old. All 13 cases prese nted features of xerostomia and xerophthalmia. The diagnosis was confirmed by po sitive Schirmer′s test, corneal fluorescein staining, and sialography. The asso ciated other dermatoses were verruca planae, pemphigus, lichen planus, vitiligo, herpes zoster, herpes simplex and systemic lupus erythematosus. All cases were treated with Chinese traditional and western medicines. Twelve cases improved ma rkedly, one eventually died of liver and renal failure and circulation failure. Conclusions The pathogenesis of Sjgren syndrome may be linked to autoimmunity, and immunological aberration has been implicated in most of associated skin dis eases. The intrinsic relationship between Sjgren syndrome and associated other dermatoses needs further investigation.