RESUMO
Background: However, lindernia species were considered as weeds, they occupy amost important place in the traditional system of medicine used worldwide especially in China.Linderniaceae is a family having high traditional medical summary with less pharmacognostical,phytochemical and biological profile. Objective: This study was designed to identify andcharacterize the phytochemical profile of different crude extracts of newly identified wholeplant Lindernia madayiparense, using gas chromatography–mass spectrometry (GC- MS).Method: Powdered plant material was extracted and evaluated for various in-vitropharmacological activities. Furthermore the potent extracts were analyzed by GC- MS. Results:The obtained Total ion chromatogram of potent extracts revealed the different types of havingsmall and moderate phytochemicals under the classification of alkaloids, glycosides, terpenoidsand phenols in major and minor amount. Conclusions: The study gives a detailed insight aboutthe phytochemical profiles of three crude extracts of Lindernia madayiparense. So thechemical entities found are may be responsible for the pharmacological activities that probablywill act as lead molecules for furthermore drug development process.
RESUMO
In recent years, there has been an exponential interest in the development of novel drug delivery systems using nanoparticles. Nanoparticles can offer significant advantages over the conventional drug delivery in terms of high stability, high specificity, high drug carrying capacity, ability for controlled release, possibility to use in different route of administration and the capability to deliver both hydrophilic and hydrophobic drug molecules. This review focuses on classification, methods of preparation, characterisation, application, advantages of nanoparticles and health perspectives.
RESUMO
The use of extended-release products offers some potential advantages in patient convenience, compliance and therapeutic outcomes. However, the range of drugs for which clinically significant advantages have been shown is limited. Prescribers and pharmacists should be aware of these products and have knowledge of their clinical use in selected patient groups. In some instances, the formulation is probably serving a marketing objective rather than a clinical objective.