RESUMO
The study was performed on 50 patients with acute myocardial infarction [MI]. Serum levels of N-terminal pro-brain natriuretic peptide [NT-proBNP] and LV functions including wall motion index [WMI] and ejection fraction [EF] were measured immediately and six weeks later after acute MI. Serum levels of NT-proBNP were significantly higher in patients [320 +/- 52 pmol/L] than controls [65 +/- 12 pmol/L] and in complicated [398 +/- 59 pmol/L] vs. Noncomplicated [170 +/- 14 pmol/L], while LV WMI and EF values were significantly lower in patients than controls and in complicated vs. non- complicated. NT-proBNP correlated significantly with both LV WMI and EF early post-infarction and after six weeks from acute MI and in patients who died during following up the study. The results revealed that NT-proBNP was highly sensitive, specific and negative predictive value for acute MI and its complications soon after and six weeks later after acute MI