RESUMO
Objective To investigate the influencing factors of kinking of extracranial internal carotid artery (EICA) in patients with transient ischemic attack. Methods Three hundred and thirty-four patients with ischemic cerebrovascular disease performed digital subtraction angiography (DSA) were chosen; they were divided into 2 groups according to vascular morphology through DSA detection: kinking group (angulation smaller than 90°, n=110) and non-kinking group (angulation larger than 90°, n=224). According to the age, the patients were divided into youth group (18-45 years old),middle age group (46-64 years old) and elderly group (older than 65 years old). The influencing factors which may be related to the kinking of EICA, including gender, age, height and stenosis degree, and the risk factors for cerebrovascular diseases were statistically analyzed. Results Univariate analysis found that the kinking group and non-kinking group on the ratio of age, gender, height, and histories of hypertension, smoking and drinking were significantly different (P＜0.05). Multiple logistic regression analysis showed that the kinking of EICA was obviously correlated to the history of hypertension (OR=2.546, 95% CI: 1.376-4.712, P=0.003) and age (taking youth group as reference group, middle age group:OR=2.610, 95% CI: 1.056-6.452, P=0.038, elderly group: OR=2.929, 95% CI: 1.159-7.401, P=0.023).Conclusion The history of hypertension and age are identified as independent predictors for kinking of EICA in patients with ischemic cerebrovascular diseases.
RESUMO
Objective To investigate the influencing factors of diagnostic time in adult moyamoya disease (MMD) and provide evidence for its early diagnosis. Methods The clinical data of 65 consecutive patients, admitted to our hopspital from August 2008 to December 2009, were retrospectively analyzed. Logistic regression nalysis was employed to confirm the relevant factors of diagnostic time. Results The 65 patients with early diagnosis and late diagnosis were 41 (63.1%) and 24 (36.9%), respectively. The percentage of patients firstly visiting a hospital with the third grade, patients with high education and high income, and patients having initial hemorrhage of the early diagnosis group was significantly higher than that in those of late diagnosis group (P<0.05). Through a logistic regression analysis, the grade of initial hospital, the level of education, initial symptom and economic level were significantly associated with the early diagnosis, and the patients having initial hemorrhage and firstly visiting a hospital with higher grade were diagnosed earlier (OR=3.401, 95%CI 1.301-8.892, P=0.013;OR=26.351, 95%CI 4.953-140.193, P=0.000). Conclusion Patients with MMD having initial hemorrhage and firstly visiting a hospital with the third grade can be early diagnosed.