RESUMO
Introduction: There are many different types of primary immunodeficiency syndromes, with an overall prevalence of one in every 2,000 children in the United States. These syndromes are broadly classified as B-cell, T-cell, phagocytic, complement, or combined immunodeficiency disorders, mainly affecting children from a very young age
Methodology: We conducted this review using a comprehensive search of MEDLINE, PubMed, and EMBASE from January 1987 to March 2017. The following search terms were used: immunodeficiency syndromes, B-cell disorder, T-cell disorder, complement disorder, phagocytic diseases, diagnosis of primary immunodeficiency, newborn screening
Aim of the work: In this study we aimed to understand the various common types of primary immunodeficiency syndromes, and also study their diagnosis and screening methods
Conclusion: Early diagnosis with the help of newborn screening and data recording can help in reducing significant mortality and morbidity of children born with such disorders. Primary health care providers and pediatricians must keep a high degree of suspicion as many times the presentation can be subtle
RESUMO
Background: Acute pharyngitis is infection of the tonsils and the pharynx and is very common among children and adolescents. They can be viral or bacterial in origin. The causative organism varies from geography, age, and season of infection. Although viral pharyngitis is more common, the complications of bacterial pharyngitis can be severe, and thus proper identification of the cause and management is very important.
Methodology: We conducted this review using a comprehensive search of MEDLINE, PubMed, and EMBASE, January 1985, through February 2017. The following search terms were used: acute pharyngitis, pediatric pharyngitis, bacterial infection, streptococcus pharyngitis, viral pharyngitis, rapid strept test, throat culture
Aim: In this review, we aim to study the common causative organisms of acute pharyngitis among pediatric population and study the best course of management that must be followed
Conclusion: Acute pharyngitis is a relatively common disease, with a viral cause most likely. An etiology due to a streptococcal infection is a major concern and should always be ruled out due to its association with significant morbidity and mortality. Long-term sequelae of streptococcal pharyngitis include rheumatic fever, rheumatic heart disease, and acute post-streptococcal glomerulonephritis