Muir-torre syndrome with different clinical presentations

The presence of sebaceous gland neoplasm and visceral malignancy is a very rare condition

We present two cases of Muir-Torre Syndrome [MTS] with different clinical presentations

The syndrome is associated with high incidence of multiple malignancies in various systems

One patient presented with a sebaceous cyst carcinoma and later with colonic neoplastic polyps while the other, after several colectomies for malignancy, developed a sebaceous cyst neoplasm

MTS is a hereditary disease; therefore, the family members may need to be counseled and screened, as early detection improves the overall prognosis and survival of the affected individual