RESUMO
Objective: To find out whether or not male gender is associated with more severe gallbladder inflammation
Study design Retrospective review of records
Place and Duration of study: Sheikh Khalifa Bin Zayed Al Nahyan [SKBZ] Hospital / CMH Muzaffarabad, from January 2012 to June 2015
Methodology: A retrospective data analysis of patients who underwent laparoscopic cholecystectomy for acute cholecystitis was done. Data for 740 patients with cholecystitis was retrieved. Out of these 220 patients who had laparoscopic cholecystectomy within 72 hours of admission, were included in the study. Gallbladder inflammation was confirmed on histopathology report
Results: There were 110 male and 110 female patients in this series. There was a significant number of male patients who had severe gallbladder inflammation in comparison with female patients [p=0.002]. The male gender was confirmed in a multivariate analysis as an independent risk factor for severe cholecystits [p=0.018]
Conclusions: Male gender is a risk for severe gall bladder inflammation. Early surgical intervention is therefore warranted to prevent complications
RESUMO
To identify non-endoscopic predictors of esophageal varices in patients with liver cirrhosis. This observational and analytical study was carried at GI and Liver Clinic, Saeed Anwar Medical Center, Dabgari Gardens, Peshawar from January 2006 to August 2006. Seventy-three patients with established cirrhosis and no history of variceal bleeding were evaluated for predetermined variables and underwent endoscopy to look for esophageal varices. Out of 73 patients, 51 [69.9%] were males and 22 [30.1%] were females. Forty-four [60.3%] patients were having esophageal varices on endoscopy and 29 [39.7%] patients were having no varices. Out of 44 patients, small varices were found in 28 [63.6%] patients while large varices were found in 16 [36.4%] patients. Platelet count <65 x 103/ mico L. serum albumin <2.2 g/dl and portal vein diameter> 13mm on ultrasound were found to have significant predictive value for large varices. Platelet count less than 65 chi 103/ micro L, serum albumin less than 2.2 g/dl and portal vein diameter more than 13 mm on ultrasound are independent and significant predictors of esophageal varices on endoscopy. Therefore screening endoscopy must be done in all patients with liver cirrhosis who have no history of GI bleeding but any of these predictors