RESUMO
Obstructive sleep apnea (OSA) is a sleep related breathing disorder associated with high morbidity and mortality. Digit ratio (2D:4D) a sexually dimorphic trait is a putative indicator of prenatal testosterone exposure and adult testosterone level. Present study aimed at investigating the correlation between 2D:4D ratio and OSA based on the study conducted on 290 volunteered participants of both the sexes in the age range of 20-45 years. A significant negative correlation was observed for 2D:4D with OSA related parameters specifically Berlin score, Epworth score and certain key anthropometric measurements, neck circumference (NC) and waist-hip ratio (WHR). The study thus showed that lower 2D:4D ratio, increases risk of developing OSA and hence it can be used as an adjunct tool in the prediction of OSA.
RESUMO
Role of free radicals in methanol toxicity was evaluated in methanol treated albino rats. Methanol intoxication increased lipid peroxidation and depleted the free radical scavenging enzyme systems. The free radical quenching effect of vitamin E protected the animals from methanol induced free radical damage.
Assuntos
Animais , Feminino , Deficiência de Ácido Fólico/metabolismo , Sequestradores de Radicais Livres/metabolismo , Radicais Livres/metabolismo , Radical Hidroxila/metabolismo , Injeções Intraperitoneais , Peroxidação de Lipídeos/efeitos dos fármacos , Fígado/efeitos dos fármacos , Masculino , Metanol/administração & dosagem , Ratos , Ratos Wistar , Vitamina E/farmacologiaRESUMO
Every year a considerable number of people die due to methly alcohol poisoning, in which most of them die even before they are given proper treatment. This report gives a simple and cheap first aid measure to those affected by methanol poisoning by the administration of activated charcoal. This study has shown that the mortality of methanol recipient rats have significantly reduced by the administration of activated charcoal.