A arte de narrar a história de uma vida em orhan pamuk: possíveis aproximações com as ideias de Sigmund Freud / The art of narrating the story of a life in orhan pamuk: possible approaches to the ideas of Sigmund Freud

Este ensaio objetiva discutir alguns trechos do livro Istambul: Memória e Cidade. Nessa obra, a arte de narrar a história de uma vida está em articular memória coletiva, trajetória singular e a hüzün, o afeto compartilhado pelos habitantes da cidade. As autoras exercitam a reflexão sobre o pensamento que está contido na arte da escrita e estabelecem possíveis aproximações "entre" dois campos diversos do saber: a literatura de Orhan Pamuk e a psicanálise de Sigmund Freud. Nessa aproximação, são destacados: a melancolia, o estranhamento e o processo de criação do romancista que faz eco com as pulsões de vida.

This paper discusses some excerpts from the book Istanbul: Memories and the City. In this work, the art of narrating the story of a life is to articulate collective memory, singular trajectory and hüzün, affection shared by the inhabitants of the city. The authors exercite reflection about the thought that is contained in the art of writing and establish possible similarities "between" two different fields of knowledge: Orhan Pamuk's literature and Sigmund Freud's psychoanalysis. In this approach, are highlighted: melancholy, alienation and the creation of the novelist that echoes the life drives process.

Immunoexpression of p53 and p16 proteins as biomarkers in oral carcinogenesis

Objective: Defects in the cell cycle control system can lead to phenotype changes and consequently to the progression of oral cancer. Thus, the aim of this study was to analyze the immunohistochemical expression of p53 and p16 and their connection with hyperplastic and neoplastic progression. Materials and Methods: Sixty-four histopathologic specimens were submitted to immunohistochemical technique to anti-p53 and anti-p16. Results: This study showed a significant increase in the level of p53 in dysplasia and oral carcinomas. Regarding p16 immunoexpression, a decrease was observed in mild to moderate dysplasia, and remained consnt between moderate dysplasia to poorly differentiated carcinoma. Conclusion: The study confirmed that the higher expression of p53 protein plays a significant role in tumor development and oral cancer progression, while the loss of p16 expression seems to be related only for the progression of carcinogenesis.Keywords: Proteins. Immunohistochemical. Genes, p53. Genes, p16. Mouth. Neoplasms.

Avaliação do desgaste da zona de perigo de molares inferiores utilizando o sistema rotatório ProTaper / Evaluation of the flaring in mandibular molars danger zone using ProTaper rotatory system

O objetivo deste estudo foi avaliar in vitro o desgaste da zona de perigo em molares inferiores, após utilização do sistema de instrumentação rotatória ProTaper. Foram utilizadas 60 raízes mesiais de molares inferiores, as quais foram divididas em 4 grupos experimentais. Um grupo foi mantido como controle e os demais foram respectivamente instrumentados com as limas SX; SX e S1; SX, S1 e S2. Os resultados foram submetidos à análise estatística, demonstrando uma diferença significante no nível de 1% entre os grupos experimentais, com um aumento do desgaste da zona de perigo diretamente proporcional ao aumento do diâmetro dos instrumentos ProTaper. Conclui-se que por não ter acontecido nenhum caso de perfuração radicular a segurança desses instrumentos no preparo de molares inferiores foi demonstrada

The aim of this study was to evaluate in vitro the flaring in mandibular molars danger zone, after root canal instrumentation with the ProTaper rotatory instrument system. Sixty extracted mandibular molars with fully formed apices had the mesial roots sectioned. The specimens were divided into four groups and instrumented until Shaping X, Shaping 1 and Shaping 2 files,respectively. One group was kept as control with no instrumentation. The results submitted to statistical analysis, showed a 1% significant difference among experimental groups, with an enlargement of the flaring in danger zone being directly proportional to the diameter of ProTaper instruments. Itis concluded that the use of this instruments on the preparation of mandibular molars is safe because there isnt any report of root perforation.