RESUMO
Food-borne botulism is a rare and serious disease caused by potent neurotoxin of the Clostridium botulinum which is a Gram-positive strictly anerobic organism. It manifests clinically as descending paralysis characterized by prominent oculo-bulbar palsies and symptoms and autonomic signs in an afebrile patient with normal sensorium. If not promptly and aggressively treated it may lead to fatality. In this communication, we report a case of food poisoning resulting in adult botulism that responded to early and effective treatment with specific antitoxin and supportive therapy. The patient made a remarkable recovery and was discharged home three weeks after admission. This case is the first to be reported for adult variant botulism in Arabian Gulf States
Assuntos
Humanos , Feminino , Adulto , Clostridium botulinum , Paralisia/diagnóstico , Doenças Transmitidas por Alimentos , Peixes/microbiologiaRESUMO
A young Kuwaiti woman presented with severe jaundice, constitutional symptoms and deranged liver function tests suggestive of hepatitis. Investigations, including a liver biopsy, showed the presence of hepatic veno-occlusive disease [HVOD] associated with antiphospholipid antibody syndrome [APS]. Clinical and laboratory abnormalities improved rapidly with anticoagulation treatment with warfarin. During the follow-up of over 1 year she remained completely normal without recurrence of symptoms. HVOD is a known but rare presentation of APS. Recognition and treatment of this condition at an early stage can be rewarding