RESUMO
Background: Endometriosis is a common gynaecological disease that affects quality of life for women. Several studies have revealed that both environmental and genetic factors contribute to the development of endometriosis. The aim of this study was to investigate the distribution of ABO and Rh blood groups in Iranian women with endometriosis who presented to two referral infertility centers in Tehran, Iran
Materials and Methods: In this case-control study, women who referred to Royan Institute and Arash Women's Hospital for diagnostic laparoscopy between 2013 and 2014 were assessed. Based on the laparoscopy findings, we categorized the women into two groups: endometriosis and control [women without endometriosis and normal pelvis]. Chi-square and logistic regression tests were used for data analysis
Results: In this study, we assessed 433 women, of which 213 patients were assigned to the endometriosis group while the remaining 220 subjects comprised the control group. The most frequent ABO blood group was O [40.6%]. The least frequent blood group was AB [4.8%]. In terms of Rh blood group, Rh+ [90.1%] was more frequent than Rh- [9.9%]. There was no significant correlation between ABO [P=0.091] and Rh [P=0.55] blood groups and risk of endometriosis. Also, there was no significant difference between the two groups with regards to the stage of endometriosis and distribution of ABO and Rh blood groups [P>0.05]
Conclusion: Although the O blood group was less dominant in Iranian women with endometriosis, we observed no significant correlation between the risk of endometriosis and the ABO and Rh blood groups. Endometriosis severity was not correlated to any of these blood groups
RESUMO
Background: Endometriosis affects women's physical and mental wellbeing. Symptoms include dyspareunia, dysmenorrhea, pelvic pain, and infertility. The purpose of this study is to assess the correlation between some relevant factors and symptoms and risk of an endometriosis diagnosis in infertile women
Materials and Methods: A retrospective study of 1282 surgical patients in an infertility Institute, Iran between 2011 and 2013 were evaluated by laparoscopy. Of these, there were 341 infertile women with endometriosis [cases] and 332 infertile women with a normal pelvis [comparison group]. Chi-square and t tests were used to compare these two groups. Logistic regression was done to build a prediction model for an endometriosis diagnosis.
Results: Gravidity [odds ratio [OR]: 0.8, confidence interval [CI]: 0.6-0.9, P=0.01], parity [OR: 0.7, CI: 0.6-0.9, P=0.01], family history of endometriosis [OR: 4.9, CI: 2.1-11.3, P0.001], history of galactorrhea [OR: 2.3, CI: 1.5-3.5, P=0.01], history of pelvic surgery [OR: 1.9, CI: 1.3-2.7, P0.001], and shorter menstrual cycle length [OR: 0.9, CI: 0.9-0.9, P=0.04] were associated with endometriosis. Duration of natural menstruation and age of menarche were not correlated with subsequent risk of endometriosis [P>0.05]. Fatigue, diarrhea, constipation, dysmenorrhea, dyspareunia, pelvic pain and premenstrual spotting were more significant among late-stage endometriosis patients than in those with early-stage endometriosis and more prevalent among patients with endometriosis than that of the comparison group. In the logistic regression model, gravidity, family history of endometriosis, history of galactorrhea, history of pelvic surgery, dysmenorrhoea, pelvic pain, dysparaunia, premenstrual spotting, fatigue, and diarrhea were significantly associated with endometriosis. However, the number of pregnancies was negatively related to endometriosis
Conclusion: Endometriosis is a considerable public health issue because it affects many women and is associated with the significant morbidity. In this study, we built a prediction model which can be used to predict the risk of endometriosis in infertile women