RESUMO
Objective To compare the efficacy of topical adapalene with topical tretinoin in the treatment of mild acne vulgaris
Methods This randomized controlled trial was conducted over a period of 6 months in outpatient department of dermatology, Lady Reading Hospital, Peshawar. 101 patients were taken after nonprobability consecutive sampling in each group. Topical adapalene 0.1% gel was given to group A while topical tretinoin 0.025%
Results Out of 202 patients, male and female patients were 91 and 111, respectively with male to female ratio 0.8:1. The age of the patients ranged from 15-25 years. Mean age in group A was 19.79 +/- 2.24 years while in group B, it was 20.11 +/- 2.53 years. Overall efficacy in adapalene group was 84.2% as compared to 39.6% of tretinoin group [p=0.000]
Conclusion Topical adapalene has a better efficacy than topical tretinoin in the treatment of mild acne vulgaris