RESUMO
Coronary artery disease (CAD) is among the main causes of death in adults. Increase of oxidative stress and defects in antioxidant defense play a major role in endothelium performance and are affecting factors in the progress of atherosclerosis. The aim of this study was to measure serum levels of uric acid (UA) and vitamin C as well as the antioxidant status in patients with CAD, and compared them with those in healthy individuals. The present case-control study was performed on 44 cases and 44 controls. Demographic data and anthropometric indices were measured. The Food Frequency Questionnaire (FFQ) and International Physical Activity Questionnaire (IPAQ) were completed. After 12 hours of fasting,10 mL blood was sampled from the participants. Serum levels of UA, vitamin C, Total Antioxidant Capacity (TAC) and Malondialdehyde (MDA) were also measured. The data were finally analyzed by SPSS v22. A significant difference was observed between the groups in terms of UA and vitamin C. However, mean levels of MDA and TAC were not significantly different between groups. The differences between groups in terms of vitamin A, vitamin E, beta-carotene, zinc and selenium intakes were not significant either. A significant difference was detected between the groups in terms of vitamin C intake. Our results suggest that increase in UA and decrease in vitamin C in serum levels can be considered as risk factors for CAD patients. Due to a lack of any significant correlation between TAC and CAD risk in this study, further study with bigger sample size is needed.
RESUMO
Coronary artery disease (CAD) is among the main causes of death in adults. Increase of oxidative stress and defects in antioxidant defense play a major role in endothelium performance and are affecting factors in the progress of atherosclerosis. The aim of this study was to measure serum levels of uric acid (UA) and vitamin C as well as the antioxidant status in patients with CAD, and compared them with those in healthy individuals. The present case-control study was performed on 44 cases and 44 controls. Demographic data and anthropometric indices were measured. The Food Frequency Questionnaire (FFQ) and International Physical Activity Questionnaire (IPAQ) were completed. After 12 hours of fasting,10 mL blood was sampled from the participants. Serum levels of UA, vitamin C, Total Antioxidant Capacity (TAC) and Malondialdehyde (MDA) were also measured. The data were finally analyzed by SPSS v22. A significant difference was observed between the groups in terms of UA and vitamin C. However, mean levels of MDA and TAC were not significantly different between groups. The differences between groups in terms of vitamin A, vitamin E, beta-carotene, zinc and selenium intakes were not significant either. A significant difference was detected between the groups in terms of vitamin C intake. Our results suggest that increase in UA and decrease in vitamin C in serum levels can be considered as risk factors for CAD patients. Due to a lack of any significant correlation between TAC and CAD risk in this study, further study with bigger sample size is needed.
RESUMO
Diagnosis of coronary artery disease [CAD] in early stages is vital in decreasing mortality by reducing the risk factors. The aim of this study was to investigate the association between erectile dysfunction [ED] and CAD. A total of 200 patients were divided into four groups according to their angiography Group 1 [G1, n = 59]: patients with one-vessel disease [1-VD]; Group 2 [G2, n = 40]: patients with two-vessel disease [2-VD]; Group 3 [G3, n = 50]: patients with three-vessel disease [3-VD]; and controls [C, n = 51] without any coronary disease. The International Index of Erectile Function [IIEF] was completed for all the patients to assess their sexual function and ED in the last 6 months. Mean age of the participants was 57.69 +/- 12.466 years. The prevalence of ED in the CAD patients was significantly higher than that of the controls [75.16% vs. 60.8%; p value = 0.041]. There was a significant direct correlation between the number of involved vessels in the CAD patients and ED severity [r: 0.183; p value = 0.010], and the ED rate increased with age. In conclusion, ED severity correlated with the number of involved vessels documented by coronary angiography. Consequently, ED may be considered a possible marker for the development of atherosclerosis and CAD
RESUMO
The rising number of women undergoing elective repeat cesarean has been one of the principal reasons for the steady increase in the cesarean delivery rate. This study aim was to assess vaginal birth rates after cesarean [VBAC] in an educational hospital at Khorramabad, Lorestan. A retrospective analysis was performed on the obstetric data from medical records of 685 deliveries that underwent cesarean section in their previous delivery. VBAC rate among women with previous cesarean section was 10.4% [71 cases]. The most frequent normal vaginal delivery was seen in women with a previous Kerr uterine incision [74.6%] and a history of one previous cesarean [69%]. VBAC delivery rate is low in our set up and proper counseling for trial of labor and evaluation of the cases of women with prior cesarean section has been considered a key method of reducing the cesarean section rate
Assuntos
Humanos , Feminino , Recesariana , Estudos RetrospectivosRESUMO
To investigate the effect of soybean on serum lipids and lipoproteins in hypercholesterolemic postmenopausal women. One hundred participants were included and divided randomly into two arms. One arm received two grams of soy every day, while the other group received similar shaped capsules filled with placebo. Subjects and outcome assessors were kept blind to the contents of the capsules. Serum cholesterol, triglyceride and low-and high-density lipoproteins were measured before and after the intervention. The two groups were similar in their baseline characteristics. We observed no favorable changes in lipid profile in either of the two groups. The two arms of the study responded similarly to the intervention and no statistically significant difference was observed between these responses. This double-blind randomized controlled trial does not support the hypothesis that the use of soybean improves serum lipid constituents in postmenopausal women having hypercholesterolemia