Research advances in signal pathway and molecular mechanism of vascular calcification / 中华老年医学杂志

Vascular disease,such as atherosclerosis and diabetic vasculopathy,is frequently complicated by vascular calcification.Previously believed to be an end-stage process of unregulated mineral precipitation,it is now well established to be a multi-faceted disease.The numerous regulatory signaling pathways that influence vascular calcification,and these pathways are directly or indirectly related to bone remodeling.This review provides a brief overview of the research progresses of vascular calcification-related molecular signaling pathways from the perspective of osteoblastic differentiation.