[Non Hodgkin's lymphoma and chronic hepatitis C virus infection: a non- fortuitous association .Two cases report]

Many authors suggest the role of hepatitis C virus [HCV] infection in the pathology of B-cell non Hodgkin's lymphomas; this is based on epidemiological, physiopathological and therapeutic arguments. The frequency of the association with hepatitis C virus infection is variable in the different study [1 to30%]. We report two cases of hepatitis C virus infection in association with non Hodgkin's lymphomas. The first case presented a low grade splenic and nodal non-Hodgkin's lymphoma associated with hepatitis C virus infection and complicated by hepato-cellular carcinoma. The second case presented a high grade nodal non-Hodgkin's lymphoma associated with HCV infection. Our cases report confirms the hypothesis of a key role of hepatitis C virus in the pathogenesis of B-cell lymphoproliferative disorders and in particular the non-Hodgkin's lymphoma. Although of several hypothesis concerning the ethiopathogenic mechanisms of this association, new studies will necessary to improve the real mechanism of this association

[Prevalence of the microscopic colitis to the course of the chronic diarrhea: about 150 cases]

The goal of our survey is to value the microscopic colitis frequency at 150 patients, colliged on a period of 6 years [1997-2003], that have a chronic diarrhea with a normal total coloscopy and that benefitted of systematic biopsies. The microscopic colitis has been recovered at 44 patients on 150 either 29,3%. 16 of our patients [37%] are put on Salazopyrine, they answered well to the treatment with a receding of 3 years. The microscopic colitis is a pathology whose frequency seems under valued, it is certainly benign but can give a frequent diarrhea requiring a curative treatment