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1.
Autops. Case Rep ; 11: e2021285, 2021. graf
Artigo em Inglês | LILACS | ID: biblio-1249016

RESUMO

Acquired Hemophagocytic Lymphohistiocytosis is a rare and deadly syndrome resulting from an overactive immune system, with uncontrolled activation of macrophages and lymphocytes, hypercytokinemia, and systemic inflammatory response. A 75-year-old male presented with typical anginal pain and was diagnosed with the acute coronary syndrome, which required a percutaneous transluminal coronary angioplasty. Instead of resolving the symptoms, the patient began to exhibit pyrexia and worsening altered sensorium with progressing renal failure, anemia, thrombocytopenia and respiratory failure. This constellation of symptoms caused the patient to require mechanical ventilation and hemodialysis. Upon laboratory analysis, hyperferritinemia provided an indication to the diagnosis of acquired hemophagocytic lymphohistiocytosis. After the initiation of dexamethasone, the patient made a significant recovery and was discharged from the hospital.


Assuntos
Humanos , Masculino , Idoso , Linfo-Histiocitose Hemofagocítica/complicações , Hiperferritinemia/diagnóstico , Dexametasona/uso terapêutico , Síndrome Coronariana Aguda/complicações , Deficiência de Glucosefosfato Desidrogenase
2.
Autops. Case Rep ; 11: e2021272, 2021. graf
Artigo em Inglês | LILACS | ID: biblio-1249024

RESUMO

Encapsulating peritoneal sclerosis occurs due to chronic irritation of the peritoneal surface resulting in inflammation and fibrosis. Encapsulating peritoneal sclerosis usually occurs in patients requiring peritoneal dialysis (PD); however, it may also occur in liver transplant patients. The fibrosis in encapsulating peritoneal sclerosis could be severe enough to cause small bowel obstruction (SBO). Herein, we report a case of encapsulating peritoneal sclerosis secondary to liver transplantation that presented with SBO. The patient was started on Tamoxifen for encapsulating peritoneal sclerosis and evaluated at follow-up without any other intestinal obstruction episodes. This case demonstrates that encapsulating peritoneal sclerosis can occur as a liver transplant complication and present with small bowel obstruction.


Assuntos
Humanos , Idoso , Doenças Peritoneais/complicações , Transplante de Fígado/efeitos adversos , Obstrução Intestinal
3.
Autops. Case Rep ; 10(1): 2019136, Jan.-Mar. 2020. ilus
Artigo em Inglês | LILACS | ID: biblio-1087661

RESUMO

Acute esophageal necrosis (AEN) also known as "black esophagus" or "acute necrotizing esophagus" is a rare entity characterized by striking endoscopic findings of circumferential black coloring of the esophagus. AEN most frequently seen in the distal esophagus and can extend proximally along the entire esophagus. Characteristically, the circumferential black mucosa stops abruptly at the EGJ. AEN tends to present as acute upper gastrointestinal bleeding, though other symptoms including dysphagia and epigastric pain have been described. The etiology of AEN is multifactorial including a combination of ischemic insult, mucosal barrier defect, and a backflow injury of gastric secretions. Described is a case of AEN in a patient with history of uncontrolled diabetes who presented with an atypical chest pain mimicking acute coronary syndrome with negative subsequent cardiovascular workup.


Assuntos
Humanos , Masculino , Idoso de 80 Anos ou mais , Doenças do Esôfago/diagnóstico , Síndrome Coronariana Aguda/diagnóstico , Dor no Peito , Necrose
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