Ethics approval: a challenge for public health researchers in India.

There is increasing impetus, interest and opportunity for people working in public health programmes in India to carry out operational research (OR) around relevant programme issues and then publish that in peer-reviewed publications. These published researches are valuable in analysing, documenting and advocating for locally generated evidence to inform policy and practice. Ethics review and approval is an essential step in the process of OR but is often viewed as a barrier rather than a prerequisite of good practice in OR. Journals and peer reviewers are also increasingly requiring approvals from local institutional ethics committees (IECs).

Mental fitness certificates: are psychiatrists in the dock.

Issuing mental fitness certificates is always a challenge for the psychiatrist. Employers tend to seek mental fitness certificates for employees who display unusual behaviour either at the workstation or at home, with the intention of safeguarding the working environment.

Victim profile and pattern of thoraco-abdominal injuries sustained in fatal road traffic accidents.

The present research aims to highlight the pattern of thoraco-abdominal injuries sustained by the victims of fatal road traffic accidents (RTA) in Manipal, South India. The study is an autopsy based observation of thoraco-abdominal injuries in victims of fatal road traffic accidents during 1999 – 2003. Road traffic accidents accounted for most of the injury related deaths (77%) during the study period. A male preponderance (86%) was observed with a male-female ratio of 6:1. Individuals in the age group of 21 to 50 years formed the most vulnerable (83%) group. External thoracic injuries were more common than internal thoracic injuries in the thoracic region. In the abdominal region, internal injuries were more common than external injuries. Lungs (61%) and kidneys (23%) were the most commonly involved organs in the thoracic and abdominal regions respectively. Majority of the victims were two wheeler occupants (35%) followed by pedestrians (23%). The study indicates the pattern of thoraco-abdominal injuries sustained along with the trend of road traffic accidents in the region.

Cancer pattern in Western Nepal: a hospital based retrospective study.

Information on cancer patterns is an important basis for determining the priorities for cancer control in different countries worldwide. There is no reliable information about the incidence or pattern of cancer in Nepal and hence an attempt was made to assess the situation based on hospital data which is the only source in the western region of Nepal. Cancer cases diagnosed by all methods or treated in Manipal Teaching Hospital, affiliated to Manipal College of Medical Sciences, Pokhara, during 1st January 2003 to 30th May 2005 were used for the present study. A total of 957 cancer cases were identified with a male to female ratio of 1.1:1. The median age of male and female patients was 63 and 60 years, respectively. The proportion of microscopically confirmed cases, both from primary and metastatic sites was 87.5% and tobacco-related cancers constituted 48% of all cancers among males and 28% among females. For males the leading cancer sites were lung (22.2%), larynx (9.8%) and stomach (9%) and that for females was lung (20%), cervix (19.7%) and breast (7.8%). Among males, 33.1% of all cancers were in the respiratory system followed by digestive organ cancers (23.2%). Among females, 28.4% cancers were related to the reproductive system, 22.8% to the respiratory system and 14.1% to digestive organs. The cancer pattern revealed by the present study provides valuable leads to cancer epidemiology in Nepal, particularly in the western region, and provides useful information for health planning and future research.

Correlation between postmortem diagnosis and survival time in poisoning deaths.

Every deaths resulting from poisoning has to be investigated to establish cause of death. Difficulties in clinical diagnosis of poisoning cases is well known because many a time they present with non specific symptoms and signs or the features may simulate natural disease process. Same with Forensic Pathologist as many times postmortem findings are nonspecific. Some poisons are retained in the body for long time after deaths while others may be rapidly destroyed during metabolic activity. This study was undertaken to find out effect of survival time on the postmortem findings, and on chemical analysis of body tissue and body fluids in poisoning deaths. In majorities of cases death was due to insecticides. Toxicological report showed positive for poison in 70% of cases. Kerosene smell, which is present in Organophosphorus poisoning, is present maximum upto three days. Chemical analysis report showed positive in 94% of cases in first three days. There after chance of detection of poison in routine viscera decreases upto 50%. Suggestions have been made for postmortem diagnosis in poisoning victims.