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Objective To retrospectively analyze the clinical characteristics of patients with malignant tumors combined with new coronavirus pneumonia (COVID-19), and to provide a scientific basis for clinical treatment. Methods SPSS 20.0 was used for data analysis. The t-test was used for quantitative data, and chi-square test/Fisher-exact test was used for qualitative data. Binary logistic regression was used for multivariate analysis, and the correlation coefficient was used for multicollinearity test before regression analysis. Results A total of 61 COVID-19 infected cancer patients were included in this study. Their average age was 62.2±12.12. The most common admission symptoms were fever (54.1%), fatigue (39.3%), and cough (37.7%). The rate of the patients with severe COVID-19 was 54.1%. Having 3 or more complications (OR: 2.07, 95%CI: 3.14-2698.12), fever (OR: 12.22, 95%CI: 1.20-86.70), low percentage of lymphocytes (OR: 15.56, 95%CI: 1.78-136.24) and low serum albumin level (OR: 254.64, 95%CI: 8.56-7576.41) were risk factors for COVID-19 severity. The fatality rate of the subjects was 8.2%, and the average hospital stay was 26.7±19.69 days. Furthermore, the severity of COVID-19 had a statistically significant impact on the average hospital stay (t=-3.48, P<0.01). Conclusion Patients with malignant tumors combined with COVID-19 have a higher severity rate, fatality rate, and average hospital stay than ordinary COVID-19 patients. Underlying diseases, fever, low lymphocyte percentage, and low serum albumin levels are the factors for the increase of the illness severity in patients with malignant tumors combined with COVID-19.
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Objective To understand the spatial and temporal distribution of HIV/AIDS in Hubei province,and provide scientific evidence for the prevention and control of AIDS.Methods GeoDa software was used for autocorrelation analysis,SatScan 9.2 software was used for statistical analysis of spatial scanning,and finally geographic information system was used for visualization.Results A total of 6 952 HIV/AIDS cases were reported during 2010-2013 in Hubei,and the spatial autocorrelation analysis showed that Global Moran's I index was 0.266 (P＜0.05),indicating that there was a positive spatial autocorrelation of HIV/AIDS.Global Moran's I index increased year by year (P＜ 0.05),indicating that the increased spatial aggregation of HIV/AIDS during 2010-2013.The local Moran's I index showed that "high-high" clustering areas were in Wuhan,and the number of "high-high" clustering areas increased during 2010-2013.Moreover,the "high-high" clustering areas expanded from Wuhan to surrounding areas.Spatial and temporal scan analysis revealed that 19 counties in Wuhan,Huangshi,Ezhou,Xianning with a radius of 60.01 km (LLR=625.14,RR=3.23) were the main spatial and temporal clustering area during 2012-2013.Conclusion The spatial changes of HIV/AIDS seemed to be regular from 2010 to 2013 in Wuhan,spatial correlation at provincial level decreased and the "high-high" clustering areas gradually expanded from Wuhan to surrounding areas,indicating that it is necessary to strengthen the AIDS prevention and control in these areas in Hubei.
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Objective To understand the spatial and temporal distribution of HIV/AIDS in Hubei province,and provide scientific evidence for the prevention and control of AIDS.Methods GeoDa software was used for autocorrelation analysis,SatScan 9.2 software was used for statistical analysis of spatial scanning,and finally geographic information system was used for visualization.Results A total of 6 952 HIV/AIDS cases were reported during 2010-2013 in Hubei,and the spatial autocorrelation analysis showed that Global Moran's I index was 0.266 (P＜0.05),indicating that there was a positive spatial autocorrelation of HIV/AIDS.Global Moran's I index increased year by year (P＜ 0.05),indicating that the increased spatial aggregation of HIV/AIDS during 2010-2013.The local Moran's I index showed that "high-high" clustering areas were in Wuhan,and the number of "high-high" clustering areas increased during 2010-2013.Moreover,the "high-high" clustering areas expanded from Wuhan to surrounding areas.Spatial and temporal scan analysis revealed that 19 counties in Wuhan,Huangshi,Ezhou,Xianning with a radius of 60.01 km (LLR=625.14,RR=3.23) were the main spatial and temporal clustering area during 2012-2013.Conclusion The spatial changes of HIV/AIDS seemed to be regular from 2010 to 2013 in Wuhan,spatial correlation at provincial level decreased and the "high-high" clustering areas gradually expanded from Wuhan to surrounding areas,indicating that it is necessary to strengthen the AIDS prevention and control in these areas in Hubei.
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Objective To explore the prevalence and influential factors of chronic respiratory system diseases among resi-dents over 1 5 years old in Hubei province and provide evidence for disease prevention.Methods During October to November in 2013,through stratified cluster sampling,we sampled 20 cities or counties.The survey included the the general condition of family, individual,chronic diseases.Results A total of 28 563 residents answered the questionnaire and 423 of them reported chronic re-spiratory system diseases by themselves.The prevalence rate was 14.8‰.These included 229 cases with COPD(54.1%),44 cases with asthma(10.4%),35 cases with chronic pharyngolaryngitis(8.3%)and 1 1 5 cases with other chronic respiratory system disea-ses(27.2%).In urban and rural area,the prevalence rate were 13.6‰ and 1 5.7‰ respectively.Multivariate logistic analysis showed that gender,age,economic status and medical insurance are influential factors of chronic respiratory system diseases.Conclusion Prevalence rate of chronic respiratory system diseases among residents over 1 5 years old in Hubei province was slightly increased and disease control measures should be brought out.
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Objective To understand the prevalence and influential factors of allergic diseases among infants aged 6-24 months in Enshi prefecture to provide the basis for the prevention of the allergic disease in infants and young children .Methods 1 724 in-fants were extracted by using multi-stage stratified cluster sampling and the data including the demographic characteristics ,family condition ,caregiver condition and behavior ,and allergic disease information were collected by the questionnaire survey .The multiva-riate Logistic regression analysis was performed to analyze the influential factors of allergic diseases .Results Among the investiga-ted infants and young children ,the prevalence of allergic diseases was 11 .83% ,which was dominated by eczema with the prevalence of 7 .54% ,followed by allergic asthma (1 .97% ) .The univariate Logistic regression analysis showed that allergic diseases were as-sociated with the nationality (χ2 =17 .865 ,P=0 .000) ,month age(χ2 =9 .420 ,P=0 .009) ,feeding patterns(χ2 =6 .304 ,P=0 .043) and ,time for adding solid food(χ2 =12 .695 ,P=0 .002) and family income(χ2 =9 .259 ,P =0 .010) .The multivariate Logistic re-gression analysis showed that the ethnic minority [OR95% CI:1 .86(1 .27~2 .73) ,P=0 .001]and artificial feeding [OR95% CI:1 .17 (1 .01~2 .82) ,P=0 .045]had the higher risk for suffering from allergic diseases ,the month age between 18 to 24 months[OR95%CI:0 .57(0 .39~0 .84) ,P=0 .005]and the family income>30 000 yuan each year [OR95% CI:0 .64(0 .43~0 .96) ,P=0 .030]were negatively correlated with the allergic diseases in infants and young children .Conclusion The prevalence of allergic diseases among infants and young children aged 6-24 months in Enshi prefecture is relatively higher and the infants of ethnic minority ,low month age ,artificial feeding and lower family income have the higher risk of allergic diseases .
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Objective To understand the schistosomiasis prevention knowledge of middle school students from areas with dif-ferent endemic levels in Hubei Province. Methods The schistosomiasis endemic regions were divided into transmission con-trolled areas and endemic controlled areas in Hubei Province,middle school students from different types of areas were selected through stratified randomized cluster sampling and were investigated by questionnaire. Results A total of 3 204 students were se-lected and investigated. The awareness rate of schistosomiasis prevention and control knowledge among the students ranged from 65.1%-90.3%. Overall,the students from endemic controlled areas had higher knowledge rates of all the items than those from transmission controlled areas(all P<0.05). The middle school students acquired schistosomiasis prevention knowledge mainly from the teachers,parents,doctors and schistosomiasis staff. Conclusion Health education to students should adopt different ways targeting at different endemic levels in the future.