Immunological studies on a bivalent inactivated oil adjuvanted vaccine against turkey rhinotracheitis virus and pasteurella multocida

The immunogenecity of combined Turkey RhinoTrachitis Virus [TRTV] and Pasterella multocida inactivated oil emulsion vaccine were evaluated in comparison to both the monovalent [TRT] and [P. Multoocida] vaccines. Sixty turkeys poults were divided into four groups, group 1, 2, and 3 were vaccinated with [TRTV], Pasterella multocida and combined [TRTV + Pasterella multocida] vaccines respectively while group 4 was kept as non vaccinated control, obtained results of cellular [Detected by lypmphocyte blastogenesis assay] and Humoral [Detected by indirect haemagglutination IHA, Enzyme linked Immuno Sorbant assay ELISA, and Serum neutralization test S.N.T] immune responses of experimentally vaccinated poults revealed that 2 successive doses of the prepared vaccines with 21 days apart produce protective immune response started at 3 weeks post vaccination and lasted for 12 weeks covering the whole fattening period

Preparation and evaluation of combined inactivated aluminium hydroxide gel vaccine against duck virus hepatitis and duck plague diseases private

A combined bivalent alhydragel vaccine against both duck plague virus [DPV] and duck virus hepatitis [DVH] was prepared. The efficacy of the new vaccine was evaluated in different groups of ducklings compared with a single vaccine against each virus alone. Evaluation depended upon estimation of both humoral and cellular immune response. The prepared combined vaccine offered a high titre against each virus. Obtained results have shown that the antibody titre obtained with the new vaccine are never inferior to the titres obtained with the separate single vaccine