1.
Chinese Journal of Biotechnology
;
(12): 1478-1488, 2017.
Artigo
em Chinês
| WPRIM
| ID: wpr-310579
RESUMO
Zn lactate and SnF₂ were used as active compounds in the dentifrice. Here, their anti-biofilm effects were evaluated on Pseudomonas aeruginosa, Acinetobacter baumannii and Streptococcus mutans. The biofilm prevention/dispersal assay of P. aeruginosa PAO1 demonstrated that Zn lactate and SnF₂ can inhibit biofilm formation independently or by combined treatment. Zn lactate disrupted extracellular polysaccharides matrix formation and SnF₂ reduced the biomass of biofilm. Most importantly, the combination of Zn lactate and SnF₂ thoroughly abolished the biofilm formation of all three strains.