Construção do guia de plantas medicinais de Florianópolis, SC, Brasil / Production of the guide to medicinal plants in Florianópolis, Santa Catarina, Brazil / Construcción de la guía de plantas medicinales de Florianópolis, Estado de Santa Catarina, Brasil

Há escassez relativa de experiências com plantas medicinais e de orientações para confecção de materiais didáticos sobre elas na Atenção Primária à Saúde (APS). Uma equipe interinstitucional (Universidade Federal de Santa Catarina e Secretaria Municipal de Saúde de Florianópolis) produziu um guia de plantas medicinais em Florianópolis, SC. O objetivo deste trabalho é apresentar essa experiência e o guia, que é voltado para profissionais da APS e que valorizou saberes científicos, populares e profissionais, evitando uma abordagem colonizadora do tema. Após alguns tópicos introdutórios, o guia apresenta 38 plantas medicinais comumente usadas em Florianópolis (nomes científicos e populares; partes usadas; fotos; características botânicas; uso popular; informações científicas; uso clínico; modo de usar; reações adversas e contraindicações; plantas na gestação; toxicidade; glossário; e referências). Espera-se contribuir para a construção de outros guias adaptados aos contextos locais e para a valorização do uso de plantas medicinais na APS. (AU)

Experiences with medicinal plants and guidance for producing educational resources about these plants for use in primary health care (PHC) are relatively scarce. A team from the Santa Catarina Federal University and Florianópolis City Council Department of Health produced the "Guide to Medicinal Plants in Florianópolis". This article presents this experience and the guide, which is aimed at PHC professionals and values scientific, traditional and professional knowledge, avoiding a colonizing approach to the topic. After presenting some introductory topics, the guide describes 38 medicinal plants commonly used in Florianópolis (scientific and common names, parts used, photo, botanical characteristics, common uses, scientific information, clinical use, adverse reactions and contraindications, plants during pregnancy, toxicity, glossary and references). It is hoped this guide will contribute to the production of other guides adapted to local contexts and recognition of the value of medicinal plants in PHC. (AU)

Hay una escasez relativa de experiencias con plantas medicinales y de orientaciones para la confección de materiales didácticos sobre ellas en la atención primaria de la salud (APS). Un equipo interinstitucional (Universidad Federal de Santa Catarina y Secretaría Municipal de Salud de Florianópolis) produjo una guía de plantas medicinales en Florianópolis, estado de Santa Catarina. El objetivo de este trabajo es presentar esa experiencia y la guía, dirigida a los profesionales de la APS y que valorizó saberes científicos populares y profesionales, evitando un abordaje colonizador del tema. Después de algunos tópicos de introducción, la guía presenta 38 plantas medicinales comúnmente utilizadas en Florianópolis (nombres científicos y populares, partes usadas, foto, características botánicas, uso popular, informaciones científicas, uso clínico, modo de usar, reacciones adversas y contraindicaciones, plantas en la gestación, toxicidad, glosario y referencias). Se espera contribuir para la construcción de otras guías adaptadas a los contextos locales y para la valorización del uso de plantas medicinales en la APS. (AU)

Investigation of Pain Mechanisms by Calcium Imaging Approaches / 神经科学通报·英文版

Due to the complex circuitry and plethora of cell types involved in somatosensation, it is becoming increasingly important to be able to observe cellular activity at the population level. In addition, since cells rely on an intricate variety of extracellular factors, it is important to strive to maintain the physiological environment. Many electrophysiological techniques require the implementation of artificially-produced physiological environments and it can be difficult to assess the activity of many cells simultaneously. Moreover, imaging Ca transients using Ca-sensitive dyes often requires in vitro preparations or in vivo injections, which can lead to variable expression levels. With the development of more sensitive genetically-encoded Ca indicators (GECIs) it is now possible to observe changes in Ca transients in large populations of cells at the same time. Recently, groups have used a GECI called GCaMP to address fundamental questions in somatosensation. Researchers can now induce GCaMP expression in the mouse genome using viral or gene knock-in approaches and observe the activity of populations of cells in the pain pathway such as dorsal root ganglia (DRG), spinal neurons, or glia. This approach can be used in vivo and thus maintains the organism's biological integrity. The implementation of GCaMP imaging has led to many advances in our understanding of somatosensation. Here, we review the current findings in pain research using GCaMP imaging as well as discussing potential methodological considerations.