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1.
Clinics in Shoulder and Elbow ; : 37-39, 2019.
Artigo em Inglês | WPRIM | ID: wpr-739750

RESUMO

Irreducible dislocation of the elbow is an uncommon event. We present the case of a posterolateral elbow dislocation after a fall injury in a 67-year-old woman. A closed reduction performed in the emergency department was unsuccessful since the limited passive range of motion resulted in difficulty to perform longitudinal traction and flexion. Computed tomography images showed that the posterolateral aspect of the capitellum was impacted by the tip of the coronoid process, thus appearing similar to the Hill-Sachs lesion in the humeral head. Subsequent open reduction of the elbow revealed the dislocation to be irreducible since the tip of the coronoid process had wedged into a triangular Hill-Sachs-like lesion in the capitellum. The joint was reduced by providing distal traction on the forearm, and main fragments were disengaged using digital pressure. At the 3-month follow-up, the patient reported no dislocations, and had an acceptable range of motion. Thus, we propose that to avoid iatrogenic injury to the joint or other nearby structures, irreducible dislocations should not be subjected to repeated manipulation.


Assuntos
Idoso , Feminino , Humanos , Luxações Articulares , Cotovelo , Serviço Hospitalar de Emergência , Seguimentos , Antebraço , Cabeça do Úmero , Articulações , Amplitude de Movimento Articular , Tração
2.
International Journal of Oral Science ; (4): 85-91, 2013.
Artigo em Inglês | WPRIM | ID: wpr-358183

RESUMO

Retaining or improving periodontal ligament (PDL) function is crucial for restoring periodontal defects. The aim of this study was to evaluate the physiological effects of low-power laser irradiation (LPLI) on the proliferation and osteogenic differentiation of human PDL (hPDL) cells. Cultured hPDL cells were irradiated (660 nm) daily with doses of 0, 1, 2 or 4 J⋅cm(-2). Cell proliferation was evaluated by the 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (MTT) assay, and the effect of LPLI on osteogenic differentiation was assessed by Alizarin Red S staining and alkaline phosphatase (ALP) activity. Additionally, osteogenic marker gene expression was confirmed by real-time reverse transcription-polymerase chain reaction (RT-PCR). Our data showed that LPLI at a dose of 2 J⋅cm(-2) significantly promoted hPDL cell proliferation at days 3 and 5. In addition, LPLI at energy doses of 2 and 4 J⋅cm(-2) showed potential osteogenic capacity, as it stimulated ALP activity, calcium deposition, and osteogenic gene expression. We also showed that cyclic adenosine monophosphate (cAMP) is a critical regulator of the LPLI-mediated effects on hPDL cells. This study shows that LPLI can promote the proliferation and osteogenic differentiation of hPDL cells. These results suggest the potential use of LPLI in clinical applications for periodontal tissue regeneration.


Assuntos
Humanos , Adenina , Farmacologia , Inibidores de Adenilil Ciclases , Fosfatase Alcalina , Genética , Efeitos da Radiação , Antraquinonas , Proteína Morfogenética Óssea 2 , Genética , Cálcio , Metabolismo , Efeitos da Radiação , Técnicas de Cultura de Células , Diferenciação Celular , Efeitos da Radiação , Linhagem Celular , Proliferação de Células , Efeitos da Radiação , Corantes , Subunidade alfa 1 de Fator de Ligação ao Core , Genética , AMP Cíclico , Efeitos da Radiação , Expressão Gênica , Efeitos da Radiação , L-Lactato Desidrogenase , Lasers Semicondutores , Terapia com Luz de Baixa Intensidade , Osteocalcina , Genética , Osteogênese , Genética , Efeitos da Radiação , Ligamento Periodontal , Biologia Celular , Efeitos da Radiação , Doses de Radiação , Reação em Cadeia da Polimerase em Tempo Real , Reação em Cadeia da Polimerase Via Transcriptase Reversa , Sais de Tetrazólio , Tiazóis
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