Chemical constituents of Periploca forrestii and their cytotoxicity activity / 中国中药杂志

<p><b>OBJECTIVE</b>To investigate the chemical constituents of the roots of Periploca forrestii and evaluate their cytotoxicity activities.</p><p><b>METHOD</b>Silica gel column chromatography was employed for the isolation and purification of chemical constituents. The structures were identified on the basis of spectral data and the cytotoxicities of compounds 2-4 were investigated by several tumors cell lines including blood tumor (HL-60, CCRT-CEM), prostate tumor (PC-3, DU-145) and Melanoma (UACC-62).</p><p><b>RESULT</b>Four compounds were isolated and identified as follows, lupeol-20(29)-en-3-nonadecanoate (1), peroiforoside I (2), 3beta,5beta,14beta-3OH-8beta-H-car-20(22)-enolide (3), perplocin (4).</p><p><b>CONCLUSION</b>Compound 1 is a new lupane triterpene fatty acid ester. Compounds 2-4 showed notable cytotoxicity against all tumor lines.</p>

Distinquishment of Armillifer and a Correction on Pathogen Misidentification from a Reported Case / 中国寄生虫学与寄生虫病杂志

A worm-like specimen recovered from a patient previously identified as Armillifer sp. in the city of Yulin,Guangxi Autonomous Region. After comparative analysis of habitat (serpents as final hosts and human being as accidental intermediate host) and body size of the 4 known pathogenic pentastomid species of Armillifer (A.agkistrodontis, A.armillatus, A.grandis and A.moniliformis) with the recovered specimen, the present authors consider that the recovered specimen has been misidentified as Armillifer sp. The recovered specimen probably belongs to a nasal leech.

Human Plerocercoidosis and Sparganosis:Ⅱ.A Historical Review on Pathology, Clinics, Epidemiology and Control / 中国寄生虫学与寄生虫病杂志

This article is the second part of the previous review and summarizes the research advances on pathol-ogy, clinical manifestation, diagnosis, treatment, epidemiology, and control of human plerocercoidosis and sparganosis.

Human Plerocercoidosis and Sparganosis :Ⅰ.A Historical Review on Aetiology / 中国寄生虫学与寄生虫病杂志

Plerocercoid should not be confused with Sparganum.The scolex of plerocercoid has a bothrium or bothrial slit but there is no true scolex in sparganum.Plerocercoid is a developmental stage of an animal tapeworm,Genus Spirometra.Sparganum is another generic name of a pseudophyllidean cestode.Plerocercoid causes benign plerocercoidosis and sparganum causes "malignant sparganosis".Plerocercoidosis is a parasitic zoonosis which can be food-borne,water-borne,contact-borne or mother-borne.During the past 20 years,there has been significant progress in studies of human plerocercoidosis and sparganosis,especially the former.Spirometra erinacei-europiea plerocercoidosis and sparganosis pro-lifera distributed mainly in East Asia.Spirometra mansonoides plerocercoidosis has been reported from the USA.Up to the present,approximately 1 400 cases of plerocercoidosis were reported from China,Japan,Korea,USA and Thailand,and at least 16 well-documented cases of human proliferating sparganosis were reported worldwide(in Japan,China,Thailand,USA,Paraguay,Venezuela,and the Philippines).The life cycle of Sparganum is unknown.For plerocercoid,human being acts as a dead-end hosts,copepod and frogs serve as intermediate hosts,and snakes and carnivorous animals are its paratenic hosts.This review summarizes the research progresss on aetiology and pathogenesis of human plerocercoidosis and sparganosis.The second part(in press) will be concentrated on their pathology,clinical manifesta-tions,diagnosis,treatment,epidemiology,control and prevention.

Discovery of a New Species of the Pentastomid Genus Porocephalus (Humboldt,1811)from Taiwan, China and its Pathogenic Features / 中国寄生虫学与寄生虫病杂志

Objective To describe the morphological characteristics of Porocephalus taiwana sp. nov., discuss its pathogenic features and the method of etiological diagnosis of the new disease. Methods Fecal sedimentation concentration was used to collect nymphs from the patient's watery stool for species identification. Clinical information was collected for determining the pathogenic features of the new infection. Results A new pathogenic pentastomid Porocephalus taiwana sp. nov. is discovered and a new disease-porocephaliasis taiwana-is nominated. With the findings from this case it is proposed that the traditional visceral pentastomiasis should be divided into two subtypes, Encystic and Excystic. According to the pathological features, this case belongs to the excystic visceral pentastomiasis. Conclusion Porocephalus taiwana sp. nov. is a new pathogenic pentastomid infecting humans. Porocephaliais taiwana belongs to a novel type (excystic) of visceral pentastomiasis.

STUDY ON THE ISOENZYME OF HAEMAPHYSALIS LONGICORNIS (NEUMANN), HYALOMMA ASIATICUM SCHULZE & SCHLOTTKE AND HYALOMMA DETRITUM SCHULZE / 重庆医科大学学报

The paper reports the isoenzyme patterns of Malic dehydrogenase, Esterase and Lactic dehydrogenase of the ixodid tick Haemaphysalis longicornis, Hyalomma asiaticum asiaticum and H. detrilum.H. longicornis:Malic dehydrogenase isoenzyme of the male, female,nymph and larva consists of 5, 6, 5 and 4 bands respectively.Esterase isoenzyme of the male, female, nymph and larva consists of 5, 5, 5 and 8 bands respectively.Lactic dehydrogenase isoenzyme of the male, female, nymph and larva consists of 3, 2, 2 and 2 bands respectively.H. asiaticum asiaticum:Malic dehydrogenase isoenzyme of the male, female, larva and egg consists of 3, 3,5 and 9 bands respectively.Esterase isoenzyme of the male, female, larva and egg consists of 6, 6, 6 and 3 bands respectively.Lactic dehydrogenase isoenzyme of the male, female, larva, and egg consists of 2, 2, 2 and 2 bands respectively.H. detritum:Malic dehydrogenase isoenzyme of the egg consists of 8 bands. Esterase isoenzyme of the egg consists of 5 bands. Lactic dehydrogenase isoenzyme of the egg consists of 2 bands