RESUMO
Background: Vertebral artery is the first branch of subclavian artery .It is an important source of blood supply to the brain. Accurate knowledge of normal and variant arterial anatomy of vertebral artery is important for clinical procedures and vascular radiology as its injury may occur at the time of cervical fracture or dislocation. The present study was done to study variant origins of vertebral artery. Aims & Objective: To study the variant origins of vertebral artery. Materials and Methods: The present study was done on thirty human cadavers to know the variant origin of vertebral arteries by Dissection method. Results: In the present study, variant origin of Left Vertebral Artery (LVA) was found in one male (3.33%) cadaver out of 30 cadavers. There was aortic origin of Left Vertebral Artery (LVA) instead of left subclavian artery. Conclusion: An understanding of anomalous origin of vertebral artery is very much important while performing diagnostic and interventional angiography & clinical improvements before vascular surgeries of supraaortic arteries.
RESUMO
Introduction: Congenital heart disease (CHD) is the most common of all the birth defects and is a leading cause of mortality in the 1st year of life. Congenital heart disease can be related to chromosomal aberrations and mutation of single gene. Material and Method: In this study a total of 24 confirmed cases of CHD were considered of age ranging from Day 1 to 15 years. A prior Written consent was taken from the parents of these patients. The relevant clinical data, important investigations and blood samples where collected. A conventional cytogenetic study was performed on the 24 selected patients. Results: Out of 24 patients 1 patient showed a chromosomal abnormality in the form of trisomy 21. Conclusion: Hence the present study was carried out as a Continued research on the genetic cause of congenital heart diseases and to augment our understanding of the mechanisms underlying the normal and abnormal development of the cardiac structures.