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Indian J Physiol Pharmacol ; 1978 Jul-Sep; 22(3): 317-20
Artigo em Inglês | IMSEAR | ID: sea-108636

RESUMO

Six basic amides were screened for local anaesthetic activity and compared with procaine and lignocaine. Amongst the basic amides screened, piperidino-N-(alpha-4-ethoxy phenyl- beta-phenyl) ethyl and Diethylamino-N (alpha-4-ethoxy- beta-phenyl) ethyl acetamide were found to be more effective as compared to lignocaine. They were found to be non-irritant, and non-toxic even in high doses.


Assuntos
Acetamidas/farmacologia , Anestésicos Locais , Animais , Cobaias , Dose Letal Mediana , Lidocaína/farmacologia , Procaína/farmacologia , Coelhos
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