Invasive skull base sphenoid mucocele

A mucocele is an epithelial lined mucus-containing sac completely filling a paranasal sinus and capable of expansion. Sphenoid mucoceles are unusual lesions, with about 130 cases reported until 2001. We present a case of a 56-year-old immunocompetent soldier with sphenoidal mucocele, documented by computed tomography and magnetic resonance imaging. The lesion was excised via translabial-transsphenoidal approach and the patient recovered completely. Early diagnosis followed by microsurgical drainage of sphenoidal mucocele and prolonged antibiotic treatment is recommended