[ comparison of osteobiol gen_oss with normal healing extraction socket in quality and quantity of bone formation for implant placement in partial edentulous patients]

The increase in the number of complex implant cases has drawn the attention of researchers toward materials having bone regeneration promoting ability. Socket preservation and bone graft are recommended to minimize bone resorption. The aim of this study was to evaluate a kind of xenograft collagenic bone [osteo biol gen_oss] in socket regeneration. This randomized clinical trial was performed in 12 cases [6 in test and 6 in control groups] with two hopeless teeth. After tooth extraction, in test group, graft material was put in sockets but in the control group the socket was healed naturally. Three months later, during implant placement the specimens from both sites were sent to a pathologist for histologic and histomorphometric evaluations. Data were analyzed using Mc Nemar and Wilcoxan sigh rank test [alpha=0.05]. There were no significant differences between two groups in foreign body reaction, inflammation, bone vitality and percentage of bone gain. Average percentage of residual graft in test site was 6.73 +/- 1.43. Osteobiol gen_oss xenograft is an appropriate biocompatible osteoconductive material that promotes bone regeneration at 3 months following socket preservation in human extraction sockets

[Effect of 660nm low power laser on pain and healing in palatal donor sites; a randomized controlled clinical trial]

Free gingival graft is one of the most predictable procedures for gingival augmentation, but patient's discomfort and pain during healing period of palatal donor site is a significant concern. The aim of this study was to evaluate the effect of 660nm low power laser on pain and healing in palatal donor sites. The present split mouth randomized controlled clinical trial was performed in 12 patients at the department of periodontics of Tehran University of Medical Sciences. Patients' allocation was done by balanced block randomization [laser group and placebo group]. In laser test group [wave length: 660 nm, power: 200mW, time of irradiation: 32s] was applied immediately post-surgery and in day 1, 2, 4 and 7 after that. In the control group, laser application was done with off power mode. Evaluation of epithelialization and healing was done with H2O2 and photograph. The number of palliative pills and bleeding was recorded. Wilcoxon test was used to analyze healing during the study. Patient's pain during study was analyzed using repeated measure ANOVA. Mc Nemar test was used to analyze bleeding. Level of statistical significance was set at 0.05. Laser group showed better epithelialization [P=0.02] and healing [P=0.01] in day 14 after surgery and showed better epithelialization in day 21[P=0.05]. No statistically differences were observed between laser group and control group in terms of bleeding and medication [P=0.51], [P=1]. According to the results of this study, the low power laser can promote palatal wound healing during the second and third week after free gingival graft procedures

Antimicrobial photodynamic therapy as an adjunctive modality in the treatment of chronic periodontitis

Due to penetration of pathogenic bacteria into the periodontal tissues in moderate to severe periodontitis, the mechanical methods are not sufficient in these cases. Therefore, administration of local/systemic antibiotic is recommended following mechanical root debridement. However, side effects of antibiotics such as microbial resistance and patient allergy led to development of alternative methods. One of the suggested methods is the antimicrobial photodynamic therapy [aPDT]. aPDT is a local non invasive treatment modality without the side effects caused by antibiotics. The aim of this study was to collect the clinical articles related to the application of aPDT in the treatment of chronic periodontitis. In order to find related clinical articles, a search of PubMed, Google Scholar and Science Direct until 2012 was performed. A total of 11 articles were found. In 7 of the 11 articles, the assessment of aPDT led to a significant improvement in the clinical attachment and probing depth. In 4 studies, there was no difference between the scaling and root planing [SRP] and adjunctive application of aPDT. aPDT in most cases resulted in less gingival bleeding compare to SRP alone. Furthermore, its application in multiple doses was more effective in comparison to a single dose treatment. It appears that aPDT is effective as an adjunctive therapy compared to conventional non_surgical treatment alone, and is recommended in multiple doses in order to achieve more appropriate results