RESUMO
Gerd is relatively uncommon in developing countries but H. pylori known to be the most common important cause of gastritis and associated with duodenal and gastric ulcers. The aim of our study was to find the relationship of H . pylori infection and GERD in Egyptian patients. The patients were selected and divided into two groups. Group I included 40 patients suffering from GERD [19 males and 21 females] and their ages ranged from [24 to 70] years; Group II, included 20 non GERD patients, with ulcerative or non ulcerative dyspepsia with H . pylori positive [12 males 8 females] and their ages ranged from [20] to [55] years. All patients were subjected to full history taking; clinical examination, laboratory investigation, endoscopic examination and three biopsies were taken from antrum of stomach to recognize H . pylori by R.U.T. and histopathological examination
Results of the present study showed that no significant positive association between H. pylori and pathogenesis of GERD where H. pylori positive with GERD occur in five patients [12.5%] especially in grade I reflux eosophagitis and H. pylori negative with GERD occur in [28] patients [70%]. There were seven patients [17.5%] with incompetent cardia and hiatus hernia hadpositive H. pylori without reflux eosophagitis. We conclude neither symptoms of GERD nor endoscopic grading of reflux eosophagitis has no relation with H. pylori infection