Study of pulmonary complications after post mastectomy radiotherapy in patients with cancer breast treated with or without simultaneous adjuvant anti - estrogen

Forty women who were treated with postmastectomy radiotherapy for breast cancer with or without adjuvant tamoxifen treatment were involved in this study. Postmastectomy radiotherapy cases showed slight restrictive ventilatory abnormalities in pulmonary functions, mainly in patients received tamoxifen treatment. The radiological abnormalities developed with postmastectomy radiotherapy were more often easily detected by high resolution computed tomography [HRCT] than by CXR and these abnormalities were significantly higher in patients received tamoxifen treatment. Postmastectomy radiotherapy encountered has in the form of pneumonitis early and late pulmonary lung fibrosis