Effecacy of CO2 laser as a therapeutic modality in treatment of condylomata accuminata

In this study, the efficacy of CO2 laser as an alternative modality in treatment of genital warts was evaluated. Twenty-two patients with anogenital warts were treated with CO2 laser under anesthesia. In 15 patients, previous conventional therapy had failed. The efficacy of the treatment was found to be 86.4%. No complications were met with any of the patients. The healing period took about 6 weeks. CO2 laser treatment is a good alternative to conventional therapy in condylomata acuminata

Stereological study of testicular biopsies of normal fertile and different infertile patients groups

Testicular biopsies from twenty-four infertile men together with three normal individuals were studied using a stereological method. The patients were classified into four groups; namely, obstructive, hypospermatogenesis, spermatocyte arrest and varicocele. The numerical density of different cells within the seminiferous epithelium were estimated. Then, the ratios of each germ cell type to Sertoli cells and the ratios between the germ cells to each other were calculated. The study showed that the number of cells and not their nuclear dimensions is the vulnerable parameter in all the infertile patient groups. Sertoli cell number was found to be constant in all groups. The normal fertile testis contained 1.846 spermatogonia, 2.12 spermatocytes, 4.638 spermatids and 4.415 sperms per Sertoli cell. In the obstructive group, sperm to Sertoli ratio was reduced than the control, while the other ratios between germ cells to Sertoli were not significantly different. The hypospermatogenesis patients group was characterized by pan germ cell hypoplasia, which was explained by a reduced number of the mother dividing cells [spermatogonia]. Spermatocyte arrest group showed an absence of spermatids and sperms and this was explained by the production of defective spermatocytes incapable for further division. Varicocele group was found to be a heterogeneous one, except for spermatocyte to Sertoli ratio, all the other germ cell ratios to Sertoli cell were reduced