Vertebro-Vertebral Fistula Occlusion Using a Woven EndoBridgeTM-Device / 신경중재치료의학

Vertebro-vertebral fistulas (VVFs) are vascular lesions that may develop after trauma or spontaneously in association with connective tissue disorders. We present a rare case of a post-traumatic VVF in a young patient presenting with a painless swelling and a bruit in her left upper neck. Digital subtraction angiography showed an arteriovenous fistula between the left vertebral artery (VA) and the vertebral venous plexus with significant steal phenomenon. Endovascular therapy was performed using a Woven EndoBridgeTM (WEB)-device combined with coils that allowed preservation of the VA. The patient fully recovered from her symptoms and follow-up imaging showed stable occlusion. In conclusion, VVFs can be effectively treated using intrasaccular flow diverters such as the WEB-device, allowing for complete and stable occlusion while preserving the parent artery.

Million Visual Analogue Scale Questionnaire: Validation of the Persian Version

STUDY DESIGN: Descriptive cross-sectional study. PURPOSE: To validate the Persian version of the Million Visual Analogue Scale Questionnaire (MVAS), a self-administered low back pain (LBP) questionnaire. OVERVIEW OF LITERATURE: The majority of LBP questionnaires translated into Persian evaluate the impact of LBP on daily living. The MVAS is one of the most commonly used self-administered LBP questionnaires, and was developed to assess a different direction and effect of activities of daily living on LBP intensity. METHODS: The questionnaire was translated into Persian with the forward-backward method and was administered to 150 patients randomly sampled from an occupational medicine clinic in Tehran in 2017. RESULTS: Cronbach's alpha for all subscales ranged between 0.670 and 0.799. Confirmatory factor analysis showed adequate construct validity of the Persian version of the MVAS, with root mean square error of approximation 0.046, goodness of fit index 0.902, and comparative fit index 0.969. Other indexes were satisfactory. CONCLUSIONS: The Persian MVAS is a valid and reliable instrument that can assess the effect of various daily activities on the intensity of LBP.

Faunal data and envenomation emergency first aid of cone snails (Conus spp.) in Qeshm Island, the Persian Gulf

OBJECTIVE@#To investigate the fauna of a highly venomous marine species group, the cone snails (Family Conidae), in the shores of Qeshm Island, of evaluating the possibility of envenomation in the area and summarize recommendations for emergency first aid.@*METHODS@#Shores surrounding Qeshm Island were surveyed to collect cone snails during cold (February and March) and warm (May and June) seasons of 2017. Collected snails were identified to the species level. Abundance and species richness were estimated in shores of different structures, including muddy and sandy-rocky shores. Also, the most updated medical literature was reviewed to summarize related emergency first aid.@*RESULTS@#Three cone snail species were recorded from southern sandy-rocky shores of the Island, in decreasing order of abundance, included crowned cone (Conus coronatus) (65%), feathered cone (Conus pennaceus) (28%), and frigid cone (Conus frigidus) (7%). Abundance of these species were significantly higher in cold season compared to the warm season (P < 0.05). No cone snails were recorded along the northern muddy shores of the Island.@*CONCLUSIONS@#Envenomation can cause various symptoms ranging from minor local pain to systemic paralysis and death due to respiratory failure. We recommend an awareness programme for the seashore visiting public.

Faunal data and envenomation emergency first aid of cone snails (Conus spp.) in Qeshm Island, the Persian Gulf

Objective To investigate the fauna of a highly venomous marine species group, the cone snails (Family Conidae), in the shores of Qeshm Island, of evaluating the possibility of envenomation in the area and summarize recommendations for emergency first aid. Methods Shores surrounding Qeshm Island were surveyed to collect cone snails during cold (February and March) and warm (May and June) seasons of 2017. Collected snails were identified to the species level. Abundance and species richness were estimated in shores of different structures, including muddy and sandy-rocky shores. Also, the most updated medical literature was reviewed to summarize related emergency first aid. Results Three cone snail species were recorded from southern sandy-rocky shores of the Island, in decreasing order of abundance, included crowned cone (Conus coronatus) (65%), feathered cone (Conus pennaceus) (28%), and frigid cone (Conus frigidus) (7%). Abundance of these species were significantly higher in cold season compared to the warm season (P < 0.05). No cone snails were recorded along the northern muddy shores of the Island. Conclusions Envenomation can cause various symptoms ranging from minor local pain to systemic paralysis and death due to respiratory failure. We recommend an awareness programme for the seashore visiting public.

[Interaction of long term calorie restriction and aerobic training programs on serum and tissue concentrations of adiponectin in male obese rats]

Introduction: the aim of present study was to investigate the interaction of aerobic training and calorie restriction on levels of adiponectin isomers in serum and abdominal fat depots in obese male rats

Materials and Methods: forty-eight wistar male rats were used as the study sample. Blood and tissue samples were collected at the 1[st], 18[th] and 28[th] weeks. After baseline sampling, the remaining 40 rats were randomly divided into control and high-fat-diet groups. The high-fat-diet group received their regimen for 18 weeks and were then randomly divided into the negative energy balance [NEB] and high-fat-diet [HFD] subgroups. NEB group alternately underwent 25% calorie restriction or aerobic training [running] with an intensity of 70 to 75% of vo2max for 10 weeks

Results: compared to the standard diet, HFD feeding increased weight and decreased retroperitoneal adipose tissue adiponectin level at the 18[th] and 28[th] weeks [P<0.05]. In comparison to the HFD, group negative energy balance in obese male rats, caused weight control with significant increase in serum levels of total and high-molecular-weight adiponectin as well as adiponectin levels in retroperitoneal and mesenteric fat depots [P<0.05]. Also insulin resistance index in line with serum concentrations of insulin, glucose and triglycerides were decreased in negative energy balance, compared to the high-fat-diet group [P<0.05]

Conclusion: this study indicates that even with simultaneous consumption of high-fat-diet, combination of aerobic training and calorie restriction can increase concentrations of adiponectin in serum and abdominal fat depots of obese male rats, and aligned with it improves lipid and metabolic profiles

Evaluation of occupational risk factors in non-hodgkin lymphoma and hodgkin's disease in Iranian men

Lymphoma is a malignancy, arises from lymphoid tissue. Nowadays, it is the ninth most common cancer in Iran. The risk factors of malignant lymphomas have not well determined, but since 20 years ago till now, too many epidemiological researches have been concerning either Non-Hodgkin Lymphoma [NHL] or Hodgkin's Disease [HD]. It is a common usual hypothesis that idiosyncratic reaction to common physical, chemical, and viral agents could lead to lymphoma without obvious immune deficiency. Some occupations has reported to cause increasing "NHL" risks, such as rubber industry, veterinaries, uranium mining, metal working, asbestos exposing, farming, textile industry, and benzene exposing. The roles of ionizing radiation, benzene and other environmental agents have not been clear, because of the lack of confirmed evidences for relation between the occupational and environmental agents with "HD". A case-control study with 150 cases of malignant lymphoma and 150 controls have performed in Tehran. Data have selected through face-to-face interviews about the medical and occupational histories. In this study, there was a significantly increased risk for Non-Hodgkin Lymphoma in these occupations; welders, metal workers, founders, aluminium workers OR=4.6[Confidence Interval [CI]: 1.47-14.35] and increased risk for Hodgkin's Disease in drivers OR=2.34[[CI]:0.86-6.35]. We have found out decreased NHL risk in office workers OR=0.54 [[CI]:0.29-1.02] and also found out a non-significant increased NHL risk in farmers OR=1.58 [[CI]:0.82-3.03]. In this study, we have found no relation between smoking and HD, or NHL. The results of this study suggest that several occupations could alter the risk of Non-Hodgkin Lymphoma and Hodgkin's Disease.

Low back pain and related factors among Iranian office workers

Low Back Pain [LBP] is likely the most common medical disorder among work population. In this survey, prevalence of LBP and pain severity and the association of them with occupational and non-occupational risk factors were specified among office workers in Baqiyatallah University Of Medical Sciences, Tehran, Iran in 2006 In this way the point prevalence of LBP and pain severity among office workers, role of some personal and occupational factors, and self-reported pain severity were assessed. The instruments used included direct interview, a body discomfort assessment tool that consisted of a 10-centimeter color Visual Analogue Scale [VAS] and a questionnaire. Face to face, interview was done for measuring of weight and height of subjects. Of 1580 volunteers, 1436 persons were participated. About 80% [79.8%] of respondents were male. Mean age of responders was 35.08 years. More than 60% had at least one episode of LBP during their working life and 45.0% of pain sufferers' first attack was during their employment. Lifetime prevalence of LBP was 92.1% and this result for last 12 months was 37.3%. Increased age up to 40 years, increased weight, sitting work style more than 4 hours, computer use more than 5 hours a day also past history of LBP had a positive association with increased like hood of occurrence of LBP. LBP had a high prevalence in office workers. This study might help to estimate low back problems in office workers and emphasize healthy lifestyle, ergonomic measurement and control, good posture and holding educational programs

[Buserelin inhibits apoptosis in male germ cells induced by busulfan in mouse testis]

The aim of this study was to investigate the effect of buserelin on apoptosis of male germ cells induced by busulfan in adult male mice. Male adult NMRI mice were divided into four group of eight each. Group 1 [control] administered PBS for 21 days subcutaneously, group 2 given 0.4 micro g buserelin for 21 days subcutaneously, group 3 given single dose of 30 mg/kg busulfan intraperitoneally and group 4 given both busulfan and buserelin for 21 days. The animals were sacrificed and their testes were dissected 35 days after the treatment. Evaluations were made by determining Johnson's score and apoptosis were assayed by terminal- deoxynucleotidyl- transferase-mediated dutp nick end labeling [TUNEL]. Statistical analyses were performed using ANOVA test. Recovery status and Johnson's score in group 4 were significantly higher than those of busulfan treated group 7.71 +/- 0.69 VS 4.46 +/- 0.56 [p< 0.001]. Apoptotic cells number cells were significantly more numerous in busulfan treated group than those of control 23.28 +/- 7.10 VS 3.54 +/- 1.02 [p<0.001]. While buserelin substantially reduced germ cell apoptosis in fourth group 10.50 +/- 2.91 in comparison with third group 23.28 +/- 7.10, [p<0.001]. Administration of buserelin after testicular damage by busulfan enhances the regeneration of spermatogenesis in mouse through inhibition of apoptosis in germ cells

[Effect of fibroblastic growth factor on resumption of meiosis, in vitro maturation and embryo development of immature mouse oocytes]

The purpose of this study was to evaluate the effect of fibroblastic growth factor on resumption of meiosis, in vitro maturation of immature mouse oocytes and resulting embryo development with and without basic fibroblastic growth factor-4 [bFGF-4].Cumulus - oocyte complex [COCs] and germinal vesicle [GV] were obtained from female NMRI mice 46-48 hours after administration of an intra-peritoneal injection of 5 IU PMSG. COCs were cultured in TCM199 supplemented with different dosages of bFGF-4. After 24 hours, metaphase II [MII] oocytes were co-incubated with sperms for 4-6 hours in 16 medium. For all groups, the rate of cleaved embryos was assessed in the T6 medium until blastocyst stage. In all compared groups, the percentage of matured MII oocytes in the 10 ng/ml [%94.4] and 20 ng/ml [%92.5] of bFGF-4 treatment groups, was significantly higher [P<0.05] than those of the control group but the percentage of embryos that developed to blastocyst in 20 ng/ml bFGF-4 treatment group was significantly higher than those of the control group [P<0.05]. Exogenous bFGF-4 improved the oocyte maturation and embryo development